IP Library Granted Patent US 8,968,653
Granted Patent B2
US 8,968,653 · App. 13/672,172 · Granted Mar 3, 2015

Sample analyzer

Inventors: Daigo Fukuma (Kobe, JP); Takaaki Nagai (Kobe, JP); Masaharu Shibata (Kobe, JP)
Assignee: Sysmex Corporation
G01N33/5094G01N33/4915G01N15/14G01N2015/1037G01N2015/1254G01N15/12G01N15/147G01N2015/0084G01N21/17G01N27/00
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Quick Facts
Patent No.
US 8,968,653
App. No.
13/672,172
Granted
Mar 3, 2015
Kind
B2
Abstract

A sample analyzer comprising: a sample preparing section for preparing first and second measurement sample including reagent and sample; a first detector for detecting a predetermined component in the first measurement sample prepared by the sample preparing section; a second detector for detecting the predetermined component in the second measurement sample prepared by the sample preparing section; and a controller configured for performing operations, comprising: (a) controlling the first detector to detect the predetermined component in the first measurement sample prepared by the sample preparing section; (b) determining the reliability of the result detected by the first detector; (c) controlling the sample preparing section to prepare the second measurement sample from the same sample when the result has been determined to be unreliable; and (d) controlling the second detector to detect the predetermined component in the second measurement sample, is disclosed.

Claims (19)

1. A sample analyzer comprising:

a sample preparing section comprising one or more chambers to prepare a measurement sample by mixing a part of a blood sample and a reagent therein:

a first detector configured to detect electronic resistance of the measurement sample so as to detect platelets;

a second detector comprising: a flow cell through which the measurement sample flows: a light emitting unit for irradiating light; and a light receiving unit for receiving light from the light emitting unit, so as to optically detect platelets; and

a controller configured to perform operations, comprising:

(a) controlling the sample preparing section to prepare a first measurement sample by mixing a first part of a blood sample and a first reagent, provide the first measurement sample to the first detector, prepare a second measurement sample by mixing a second part of the blood sample and a second reagent, and provide the second measurement sample to the second detector;

(b) obtaining a first result, detected by the first detector, regarding platelets in the first measurement sample, and obtaining a second result, detected by the second detector, regarding platelets in the second measurement sample;

(c) determining reliability of the first result and the second result;

(d) when the first and second results have been determined to be unreliable, controlling the second detector to change a detection sensitivity of the light receiving unit;

(e) controlling the sample preparing section to prepare a third measurement sample by using a third part of the blood sample, and provide the third measurement sample to the second detector; and

(f) obtaining a third result, detected by the second detector, regarding platelets in the third measurement sample.

2. The sample analyzer according to claim 1 , wherein the second detector detects light scattering of the second measurement sample.

3. The sample analyzer according to claim 1 , wherein the light receiving unit comprises a detecting part for detecting light and for outputting signal corresponding to an amount of detected light, and an amplifier for amplifying the signal output from the detecting part; and the detection sensitivity relates to the level of amplification by the amplifier.

4. The sample analyzer according to claim 1 , wherein the third reagent has different composition from the second reagent.

5. The sample analyzer according to claim 1 , wherein

the controller is configured to obtain a platelet count value by the first measurement as the first result and

a frequency distribution of platelets by the second measurement as the second result.

6. The sample analyzer according to claim 5 , wherein

in step (d), the controller determines the first result is unreliable when the platelet count value is less than the predetermined value, and the second result is unreliable when the frequency distribution of platelets is abnormal.

Priority Claims (1)
JP 2008-276637 · Oct 28, 2008 · national
Continuity (2)
Continuation 12605850 · Oct 26, 2009
Related Publication 20130065317A1 · Mar 14, 2013