Method for qualifying a non-particulate ion-exchanger adsorber
The present invention relates to a method for the validation of a non-particulate ion exchange adsorber and a kit for the validation of a non-particulate ion exchange adsorber.
1. A method for validation of a non-particulate anion exchange adsorber, with anion-exchanging groups, comprising the steps of
loading the non-particulate adsorber with alkali solution,
rinsing the non-particulate anion exchange adsorber with water,
loading the adsorber with a liquid, ion-containing acid and detecting a concentration of the ions that have broken through by means of an ion-sensitive probe to determine a concentration profile, and
comparing the determined concentration profile with a concentration profile of a non-particulate ion exchange adsorber of known integrity.
2. A method for validation of a non-particulate cation exchange adsorber, with cation-exchanging groups, comprising the steps of
loading the non-particulate adsorber with acid,
rinsing the non-particulate ion exchange adsorber with water,
loading the adsorber with a liquid, ion-containing alkali solution and detecting a concentration of the ions that have broken through by means of an ion-sensitive probe to determine a concentration profile, and
comparing the determined concentration profile with a concentration profile of a non-particulate ion exchange adsorber of known integrity.
3. The method of claim 2 , wherein the ion-sensitive probe is a pH electrode, an ion-sensitive field effect transistor or a pH indicator dye.
4. The method of claim 1 , wherein the ion-sensitive probe is a pH electrode, an ion-sensitive field effect transistor or a pH indicator dye.