IP Library › Granted Patent US 9,193,763
Granted Patent B2
US 9,193,763 · App. 12/673,931 · Granted Nov 24, 2015

PSMA binding ligand-linker conjugates and methods for using

Inventors: Philip Stewart Low (West Lafayette, IN); Sumith A. Kularatne (San Diego, CA)
Assignee: Purdue Research Foundation
C07K5/08A61K47/48023A61K47/48038A61K47/48084A61K49/0041A61K49/0043A61K49/0056A61K51/04A61K51/0402A61K51/0489C07C323/52C07D207/416
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Quick Facts
Patent No.
US 9,193,763
App. No.
12/673,931
Granted
Nov 24, 2015
Kind
B2
Abstract

Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

Claims (4)

1. A conjugate selected from the group consisting of

2. A conjugate of the formula

3. A salt of a conjugate of the formula

4. A salt of a conjugate selected from the group consisting of

Continuity (3)
Provisional Application 61074358 · Jun 20, 2008
Provisional Application 60956489 · Aug 17, 2007
Related Publication 20100324008A1 · Dec 23, 2010