Wound dressing devices and methods
The present invention provides an absorbent wound dressing assembly that can be used to stanch, seal, or stabilize a site of tissue injury, tissue trauma, or tissue access. The wound dressing assembly is flexible so that it can be adapted and used to fit in narrow and small wound sites. Generally the wound dressing assembly comprises a flexible carrier material that is impregnated with a non-mammalian material for control of severe bleeding. The preferred non-mammalian material is poly [β-(1→4)-2-amino-2-deoxy-D-glucopyranose] more commonly referred to as chitosan.
1. A hemostatic article comprising:
a nonwoven mesh composed of fibers of a polymeric material, wherein the polymeric material is a blend of rayon and polyester; and
an interpenetrating network of a dried chitosan solution, wherein the interpenetrating network is in the form of webs anchored among various fibers of the polymeric material and wherein the dried chitosan solution has a moisture content of less than 4.36 weight percent; and
wherein the hemostatic article has a permeability to blood (mean flow rate) of 0.15-0.35 ml/s and a Gurley stiffness value (in units of milligrams) of 500-6,000.
2. The hemostatic article of claim 1 , wherein the weight ratio of rayon to polyester in the polymeric material is in the range of from about 1:3 to about 3:1.
3. The hemostatic article of claim 1 , wherein the weight ratio of rayon to polyester in the polymeric material is in the range of from about 1:4 to about 3:4.
4. The hemostatic article of claim 1 , wherein the dried chitosan solution has a moisture content of less than 3.12 weight percent.
5. The hemostatic article of claim 1 , wherein the dried chitosan solution has an acid content of 1.8-2.1 weight percent.
6. A wound dressing assembly comprising the hemostatic article of claim 1 and an adhesive layer.