IP Library Granted Patent US 9,226,940
Granted Patent B2
US 9,226,940 · App. 14/307,684 · Granted Jan 5, 2016

Method of treating ocular disorders

Inventor: Richard Roberts (Johnston, IA)
Assignee: Kemin Industries, Inc.
A61K33/34A61K31/00A61K31/015A61K31/047A61K31/05A61K31/07A61K31/085A61K31/11A61K31/352A61K31/353A61K31/355A61K31/375A61K33/04A61K33/30A61K45/06
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Quick Facts
Patent No.
US 9,226,940
App. No.
14/307,684
Granted
Jan 5, 2016
Kind
B2
Abstract

A method wherein subjects having or at risk for having hyperopia, presbyopia or astigmatism are administered a composition having an effective amount of ocular antioxidants, including specifically macular pigments, to prevent, treat, or delay the onset of age-related macular degeneration (AMD).

Claims (13)

1. A method of reducing the increased blue and ultraviolet light damage to the retina of a subject having a condition that causes such blue or ultraviolet light to fall disproportionally on or in front of the retina relative to the blue and ultraviolet light damage present in a subject having no such condition, wherein the condition is presbyopia or hyperopia or astigmatism, comprising administering to the subject having such condition a composition comprising a therapeutically effective amount of one or more ocular antioxidants.

2. The method of claim 1 , wherein said ocular antioxidant is selected from the group consisting of antioxidant vitamins, carotenoids, antioxidant minerals, natural antioxidant extracts and synthetic antioxidants.

3. The method of claim 2 , wherein said antioxidant vitamin is selected from the list consisting of vitamins A, C, and E.

4. The method of claim 2 , wherein said carotenoid is selected from the list consisting of lutein, zeaxanthin, beta-carotene, retinoids, retinal, retinaldehyde, and meso-zeaxanthin.

5. The method of claim 2 , wherein said antioxidant mineral is selected from the list consisting of zinc, copper, and selenium.

6. The method of claim 2 , wherein said natural extract is selected from the list consisting of polyphenols, quercitin, anthocyanins, and anthocyanidins.

7. The method of claim 2 , wherein said synthetic antioxidant is selected from the list consisting of BHT, BHA, and BTHQ.

8. The method of claim 2 , wherein said therapeutically effective amount of said antioxidant vitamin is between 0.02 (1 IU) and 15 mg (150 IU) per kilogram of body weight of said subject per day.

9. The method of claim 2 , wherein said therapeutically effective amount of said carotenoid is between 0.0001 and 2 mg per kilogram of body weight of said subject per day.

10. The method of claim 2 , wherein said therapeutically effective amount of said antioxidant mineral is between 0.0001 and 5 mg per kilogram of body weight of said subject per day.

11. The method of claim 2 , wherein said therapeutically effective amount of said synthetic antioxidant is between 0.001 and 15 mg per kilogram of body weight of said subject per day.

12. The method of claim 2 , wherein said therapeutically effective amount of said natural extract is between 0.0001 and 20 mg per kilogram of body weight of said subject per day.

13. The method of claim 2 , wherein said therapeutically effective amount of said synthetic antioxidant is between 0.0001 and 20 mg per kilogram of body weight of said subject per day.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jul 6, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: KEMIN FOODS, L.C.; KEMIN HOLDINGS, L.C.; KEMIN INDUSTRIES, INC.
Reel/Frame 075184/0539 →
IP SUPPLEMENT (PATENTS) Recorded Apr 15, 2016
From: KEMIN FOODS, L.C.; KEMIN INDUSTRIES, INC.; KEMIN HOLDINGS, L.C.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 038439/0522 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 1, 2015
From: ROBERTS, RICHARD
To: KEMIN INDUSTRIES, INC.
Reel/Frame 037179/0322 →
Continuity (3)
Division 13238939 · Sep 21, 2011
Provisional Application 61384958 · Sep 21, 2010
Related Publication 20140302169A1 · Oct 9, 2014