IP Library Granted Patent US 9,249,174
Granted Patent B2
US 9,249,174 · App. 14/135,488 · Granted Feb 2, 2016

Substituted nucleosides, nucleotides and analogs thereof

Inventors: Leonid Beigelman (San Mateo, CA); Guangyi Wang (Carlsbad, CA); David Bernard Smith (San Mateo, CA)
Assignee: Alios BioPharma, Inc.
C07H19/06C07H19/10C07H19/16C07H19/173C07H19/20C07H19/207C07H19/213
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Quick Facts
Patent No.
US 9,249,174
App. No.
14/135,488
Granted
Feb 2, 2016
Kind
B2
Abstract

Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.

Claims (14)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt of the foregoing.

2. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

3. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

4. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

5. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

6. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

7. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2023
From: JANSSEN PHARMACEUTICA NV
To: JANSSEN PHARMACEUTICALS, INC.
Reel/Frame 063601/0311 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2022
From: JANSSEN BIOPHARMA, LLC
To: JANSSEN PHARMACEUTICA NV
Reel/Frame 060020/0633 →
CHANGE OF NAME Recorded Oct 1, 2020
From: ALIOS BIOPHARMA, INC.
To: JANSSEN BIOPHARMA, INC.
Reel/Frame 053968/0536 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 13, 2014
From: BEIGELMAN, LEONID; WANG, GUANGYI; SMITH, DAVID BERNARD
To: ALIOS BIOPHARMA, INC.
Reel/Frame 031950/0333 →
Continuity (3)
Provisional Application 61890125 · Oct 11, 2013
Provisional Application 61745466 · Dec 21, 2012
Related Publication 20140179910A1 · Jun 26, 2014