IP Library Granted Patent US 9,265,809
Granted Patent B2
US 9,265,809 · App. 14/304,808 · Granted Feb 23, 2016

Methods and compositions for treating and preventing signs or symptoms of eye disease

Inventor: Leonidas A. Johnson (Diamond Bar, CA)
Assignee: Johnson Living Trust dated October 26, 2011, Leonidas A. Johnson, Trustee
A61K36/28A61K9/0048A61K9/08A61K31/352A61K31/416A61K31/417A61K31/4172A61K31/616A61K45/06
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Quick Facts
Patent No.
US 9,265,809
App. No.
14/304,808
Granted
Feb 23, 2016
Kind
B2
Abstract

Compositions and methods for the treatment and prevention of at least one of a sign and a symptom associated with an eye disease are disclosed. Preferred compositions could comprise a liquid formulation including Cineraria maritima and at least one of a nonsteroidal anti-inflammatory drug, a carnosine, and a cannabinoid.

Claims (13)

1. A method of treating cataracts in a human in need thereof comprising:

preparing a Cineraria maritima extract using at least one of a dry portion, a fresh succus portion, a fresh emulsified portion, and a liquefied portion of a Cineraria maritima plant;

adding acetylsalicyclic acid, N-acetylcarnosine and purified delta-9-tetrahydrocannabinol to the Cineraria maritima extract to produce an ophthalmic composition; and

administering a therapeutically effective amount of the ophthalmic composition into the eye of the human in need thereof.

2. The method of claim 1 , wherein administering the therapeutically effective amount comprises administering the ophthalmic composition as an eye drop.

3. The method of claim 1 , wherein administering the therapeutically effective amount comprises placing an ocular insert in an eye of the human.

4. The method of claim 1 , wherein adding acetylsalicyclic acid, N-acetylcarnosine and purified delta-9-tetrahydrocannabinol to the Cineraria maritima extract comprises adding 0.05-1% acetylsalicylic acid, 1% N-acetylcarnosine, and 1% Cannabis Sativa L.

5. The method of claim 4 , wherein the ophthalmic composition comprises between 0.0001 and 10 vol %, inclusive, of each of the 0.05-1% acetylsalicylic acid, the 1% N-acetylcarnosine and the 1% Cannabis Sativa L.

6. The method of claim 1 , further comprising adding at least one of a buffer, a viscolizer, and a preservative to the Cineraria maritima extract to produce the ophthalmic composition.

7. The method of claim 1 , further comprising oxyacetic acid to the Cineraria maritima extract to produce the ophthalmic composition.

8. The method of claim 1 , further comprising apportioning the ophthalmic composition into at least one of a plurality of eye dropper bottles, a plurality of preservative free vials, and a plurality of ocular inserts.

9. The method of claim 1 , further comprising obtaining a Cineraria maritima tincture, and wherein preparing the Cineraria maritima extract comprises preparing the Cineraria maritima extract using the Cineraria maritima tincture.

10. The method of claim 1 , further comprising adding Bendazac to the Cineraria maritima extract to produce the ophthalmic composition.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 18, 2014
From: JOHNSON, LEONIDAS A
To: JOHNSON LIVING TRUST DATED OCTOBER 26, 2001, LEONIDAS A JOHNSON, TRUSTEE
Reel/Frame 033127/0479 →
Continuity (3)
Provisional Application 61889343 · Oct 10, 2013
Provisional Application 61888871 · Oct 9, 2013
Related Publication 20150099019A1 · Apr 9, 2015