Tissue engineered blood vessel

Inventors: Kevin Cooper (Flemington, NJ); Iksoo Chun (Princeton, NJ); David C. Colter (Hamilton, NJ); Sridevi Dhanaraj (Raritan, NJ); Anna Gosiewska (Skillman, NJ); Agnieszka Seyda (Belle Mead, NJ); Carrie H. Fang (Pittstown, NJ); Chunlin Yang (Belle Mead, NJ)

Assignee: CORDIS CORPORATION

C12N5/0691 A61L27/18 A61L27/3604 A61L27/38 A61L27/507

View Patent ↗

Loading inventors, assignments & file history…

Monitor This Case

Get email alerts when status or documents change.

Order Certified Copies

Most orders are placed with the USPTO same day — all within 24 business hours.

Order via The Patent Place →

Pre-filled with this patent's details

Quick Facts

Patent No.: US 9,290,742
App. No.: 13/799,520
Granted: Mar 22, 2016
Kind: B2

External Links

USPTO Patent Center↗ Full Patent PDF↗

Abstract

Compositions and methods of using tissue engineered blood vessels to repair and regenerate blood vessels of patients with vascular disease are disclosed.

Claims (6)

1. A method of making a tissue engineered blood vessel comprising the steps of:

a. Providing a scaffold comprising a solution of poly(p-dioxanone) and 1,1,1,3,3,3-hexafluoro-2-propanol solvent formed as an electrospun tubular scaffold of randomly oriented fibers;

b. Cutting the electrospun tubular scaffold to form a scaffold sheet;

c. Seeding said scaffold sheet with cells;

d. Rolling said seeded sheet into a tube; and

e. Culturing the tube in a bioreactor.

Assignments (5)

SECURITY INTEREST Recorded Oct 1, 2025

From: CORDIS US CORP.; ACCESS CLOSURE, LLC

To: HPS INVESTMENT PARTNERS, LLC

Reel/Frame 072973/0157 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 1, 2025

From: CARDINAL HEALTH SWITZERLAND 515 GMBH; CARDINAL HEALTH 529, LLC; CORDIS CORPORATION; FLEXIBLE STENTING SOLUTIONS, INC

To: CORDIS US CORP