IP Library Granted Patent US 9,295,263
Granted Patent B2
US 9,295,263 · App. 14/826,157 · Granted Mar 29, 2016

Methods of use of seed-origin endophyte populations

Inventors: Geoffrey von Maltzahn (Boston, MA); Richard Bailey Flavell (Thousand Oaks, CA); Gerardo V. Toledo (Belmont, MA); Slavica Djonovic (Malden, MA); Luis Miguel Marquez (Belmont, MA); David Morris Johnston (Cambridge, MA); Yves Alain Millet (Newtonville, MA); Jeffrey Lyford (Hollis, NH); Alexander Naydich (Cambridge, MA); Craig Sadowski (Somerville, MA)
Assignee: Symbiota, Inc.
A01N63/02A01C1/06A01N63/00A01C1/00
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Quick Facts
Patent No.
US 9,295,263
App. No.
14/826,157
Granted
Mar 29, 2016
Kind
B2
Abstract

This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.

Claims (24)

1. A method for increasing tolerance to drought of a cereal agricultural plant, said method comprising:

(a) contacting seed of said plant with a composition comprising a purified bacterial population that comprises a first bacterial endophyte and a second bacterial endophyte, wherein the first bacterial endophyte and second bacterial endophyte has a 16S nucleic acid sequence that is at least 97% identical to a 16S nucleic acid sequence selected from the group consisting of SEQ ID NO: 521, 533, 560, 588, 658, and 856, wherein the first bacterial endophyte and the second bacterial endophyte are of different genera and have different 16S nucleic acid sequence,

(b) and growing said seed to produce plants colonized with the endophyte bacteria, wherein the plants have increased tolerance to drought stress as compared to a reference plant grown under the same conditions.

2. The method of claim 1 , wherein the bacterial endophyte is obtainable from a different cultivar, variety or crop as compared to the seed.

3. The method of claim 1 , wherein the bacterial endophyte colonizes the roots of the cereal agricultural plant.

4. The method of claim 1 , wherein the composition further comprises a purified fungal population.

5. The method of claim 1 , wherein the purified bacterial population comprises more than two bacterial endophytes.

6. The method of claim 1 , wherein the bacterial endophyte is obtainable from an interior seed compartment.

7. The method of claim 1 , wherein the bacterial endophyte is obtainable from an exterior surface of a seed.

8. The method of claim 1 , wherein the bacterial endophyte is obtained from a rice seed.

9. The method of claim 1 , wherein the bacterial endophyte is obtained from a maize seed.

10. The method of claim 1 , wherein the bacterial endophyte is obtained from a wheat seed.

11. The method of claim 1 , wherein the bacterial endophyte is obtained from a barley seed.

12. A method for increasing tolerance to oxidative stress of a cereal agricultural plant, said method comprising

(a) contacting seed of said plant with a composition comprising a purified bacterial population that comprises a first bacterial endophyte and a second bacterial endophyte, wherein the first bacterial endophyte and second bacterial endophyte has a 16S nucleic acid sequence that is at least 97% identical to a 16S nucleic acid sequence selected from the group consisting of SEQ ID NO: 521, 533, 560, 588, 658, and 856, wherein the first bacterial endophyte and the second bacterial endophyte are of different genera and have different 16S nucleic acid sequence,

(b) and growing said seed to produce plants colonized with the endophyte bacteria, wherein the plants have increased tolerance to oxidative stress as compared to a reference plant grown under the same conditions.

13. The method of claim 12 , wherein the bacterial endophyte is obtainable from a different cultivar, variety or crop as compared to the seed.

14. The method of claim 12 , wherein the bacterial endophyte colonizes the roots of the cereal agricultural plant.

15. The method of claim 12 , wherein the composition further comprises a purified fungal population.

16. The method of claim 12 , wherein the purified bacterial population comprises more than two bacterial endophytes.

17. The method of claim 12 , wherein the bacterial endophyte is obtained from a rice seed.

18. The method of claim 1 , wherein the bacterial endophyte is obtained from a maize seed.

19. The method of claim 1 , wherein the bacterial endophyte is obtained from a wheat seed.

20. The method of claim 1 , wherein the bacterial endophyte is obtained from a barley seed.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Oct 25, 2023
From: CORTLAND CAPITAL MARKET SERVICES LLC
To: INDIGO AG, INC.; INDIGO AGRICULTURE, INC.
Reel/Frame 065344/0780 →
SECURITY INTEREST Recorded Aug 10, 2023
From: INDIGO AGRICULTURE, INC.; INDIGO AG, INC.
To: CORTLAND CAPITAL MARKET SERVICES LLC, AS AGENT
Reel/Frame 064559/0438 →
SECURITY INTEREST Recorded Sep 29, 2020
From: CORTLAND CAPITAL MARKET SERVICES LLC
To: INDIGO AGRICULTURE, INC.; INDIGO AG, INC.
Reel/Frame 053926/0211 →
CHANGE OF NAME Recorded Aug 5, 2016
From: SYMBIOTA, INC.
To: INDIGO AG, INC.
Reel/Frame 039600/0612 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2015
From: VON MALTZHAN, GEOFFREY; FLAVELL, RICHARD; TOLEDO, GERARDO V.; DJONOVIC, SLAVICA; MARQUEZ, LUIS MIGUEL; JOHNSTON, DAVID MORRIS; MILLET, YVES ALAIN; LYFORD, JEFFREY; NAYDICH, ALEXANDER; SADOWSKI, CRAIG
To: SYMBIOTA, INC.
Reel/Frame 037327/0312 →
Continuity (11)
Continuation 14704891 · May 5, 2015
Continuation 14316469 · Jun 26, 2014
Provisional Application 61957255 · Jun 26, 2013
Provisional Application 61959859 · Sep 4, 2013
Provisional Application 61959847 · Sep 4, 2013
Provisional Application 61959858 · Sep 4, 2013
Provisional Application 61959854 · Sep 4, 2013
Provisional Application 61959861 · Sep 4, 2013
Provisional Application 61959870 · Sep 4, 2013
Provisional Application 61935761 · Feb 4, 2014
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