Low water content soft lens for eye, and method for producing the same
A low water content soft lens for eye is provided, which includes a layer made of an acidic polymer and a basic polymer on at least a part of a surface of a base material containing a polysiloxane compound. Adhesion of the lens to the cornea during wear, which has hitherto been regarded as a problem in a conventional low water content soft lens for eye, can be reduced or avoided when using the low water content soft lens.
1. A low water content soft lens for eye, comprising a base material, a layer made of an acidic polymer and a basic polymer being formed on at least a part of a surface of the base material,
wherein the water content of the lens is 1% or less;
wherein the layer made of an acidic polymer and a basic polymer is composed of one layer made of an acidic polymer and one layer made of a basic polymer, so two layers in total; or the layer made of an acidic polymer and a basic polymer is composed of one or two layers made of an acidic polymer, and one or two layers made of a basic polymer, and three layers in total;
wherein the base material contain, as a main component, a polymer of the following component A, or a copolymer of the following components A and B:
component A: a polysiloxane compound which has a plurality of polymerizable functional groups per molecule, and also has a number average molecular weight of 6,000 or more, and
component B: a polymerizable monomer having a fluoroalkyl group;
the component A is a polysiloxane compound represented by the following formula (A1):
wherein X 1 and X 2 each independently represents a polymerizable functional group; R 1 to R 8 each independently represents a substituent selected from hydrogen, an alkyl group having 1 to 20 carbon atoms, a phenyl group and a fluoroalkyl group having 1 to 20 carbon atoms; L 1 and L 2 each independently represents a divalent group; and a and b each independently represents the number of the respective repeating units, and X 1 and X 2 in the formula (A1) are (meth)acryloyl groups,
the layer made of an acidic polymer and a basic polymer contains two or more kinds of acidic polymers and one or more kinds of basic polymers.
2. The low water content soft lens for eye according to claim 1 , wherein the base material contains 5% by weight or more of silicon atoms.
3. The low water content soft lens for eye according to claim 1 , wherein the component B is a (meth)acrylic acid fluoroalkyl ester.
4. The low water content soft lens for eye according to claim 1 , wherein at least one kind among the acidic and basic polymers is a polymer having a group selected from a hydroxyl group and an amide bond.
5. The low water content soft lens for eye according to claim 4 , wherein at least one kind among the acidic and basic polymers is a polymer having a hydroxyl group.
6. The low water content soft lens for eye according to claim 1 , wherein L1 and L2 are divalent groups having 1 to 20 carbon atoms represented by the following formulas (LE1) or (LE3):
OCH2CH2CH2 (LE1)
OCH2CH2NHCOOCH2CH2CH2 (LE3).
7. A low water content soft lens for eye, comprising a base material, a layer made of an acidic polymer and a basic polymer being formed on at least a part of a surface of the base material, wherein the water content of the lens is 1% or less;
wherein the layer made of an acidic polymer and a basic polymer is composed of one layer made of an acidic polymer and one layer made of a basic polymer, so two layers in total; or the layer made of an acidic polymer and a basic polymer is composed of one or two layers made of an acidic polymer, and one or two layers made of a basic polymer, and three layers in total;
wherein the base material contain, as a main component, a polymer of the following component A, or a copolymer of the following components A and B:
component A: a polysiloxane compound which has a plurality of polymerizable functional groups per molecule, and also has a number of average molecular weight of 6,000 or more, and
component B: a polymerizable monomer having a fluoroalkyl group;
the component A is a polysiloxane compound represented by the following formula (A1):
wherein X 1 and X 2 each independently represents a polymerizable functional group; R 1 to R 8 each independently represents a substituent selected from hydrogen, an alkyl group having 1 to 20 carbon atoms, a phenyl group and a fluoroalkyl group having 1 to 20 carbon atoms; L 1 and L 2 each independently represents a divalent group; and a and b each independently represents the number of the respective repeating units, and X 1 and X 2 in the formula (A1) are (meth)acryloyl groups; and
wherein two or more kinds among the acidic and basic polymers are polymers having a group selected from a hydroxyl group and an amide bond.
8. The low water content soft lens for eye according to claim 7 , wherein the base material contains 5% by weight or more of silicon atoms.
9. The low water content soft lens for eye according to claim 7 , wherein the component B is a (meth)acrylic acid fluoroalkyl ester.
10. The low water content soft lens for eye according to claim 7 , wherein at least one kind among the acidic and basic polymers is a polymer having a hydroxyl group.
11. The low water content soft lens for eye according to claim 7 , wherein L 1 and L 2 are divalent groups having 1 to 20 carbon atoms represented by the following formulas (LE1) or (LE3):
OCH 2 CH 2 CH 2 (LE1)
OCH 2 CH 2 NHCOOCH 2 CH 2 CH 2 (LE3).
12. A low water content soft lens for eye, comprising a base material, a layer made of an acidic polymer and a basic polymer being formed on at least a part of a surface of the base material, wherein the water content of the lens is 1% or less;
wherein the layer made of an acidic polymer and a basic polymer is composed of one layer made of an acidic polymer and one layer made of a basic polymer, so two layers in total; or the layer made of an acidic polymer and a basic polymer is composed of one or two layers made of an acidic polymer, and one or two layers made of a basic polymer, and three layers in total;
wherein the base material contain, as a main component, a polymer of the following component A, or a copolymer of the following components A and B:
component A: a polysiloxane compound which has a plurality of polymerizable functional groups per molecule, and also has a number of average molecular weight of 6,000 or more, and
component B: a polymerizable monomer having a fluoroalkyl group;
the component A is a polysiloxane compound represented by the following formula (A1):
wherein X 1 and X 2 each independently represents a polymerizable functional group; R 1 to R 8 each independently represents a substituent selected from hydrogen, an alkyl group having 1 to 20 carbon atoms, a phenyl group and a fluoroalkyl group having 1 to 20 carbon atoms; L 1 and L 2 each independently represents a divalent group; and a and b each independently represents the number of the respective repeating units, and X 1 and X 2 in the formula (A1) are (meth)acryloyl groups; and,
wherein the acidic polymer comprises a polymer having a group selected from an amide bond and a hydroxyl group.
13. The low water content soft lens for eye according to claim 12 , wherein the base material contains 5% by weight or more of silicon atoms.
14. The low water content soft lens for eye according to claim 12 , wherein the component B is a (meth)acrylic acid fluoroalkyl ester.
15. The low water content soft lens for eye according to claim 12 , wherein at least one kind among the acidic and basic polymers is a polymer having a hydroxyl group.
16. The low water content soft lens for eye according to claim 12 , wherein L 1 and L 2 are divalent groups having 1 to 20 carbon atoms represented by the following formulas (LE1) or (LE3):
OCH 2 CH 2 CH 2 (LE1)
OCH 2 CH 2 NHCOOCH 2 CH 2 CH 2 (LE3).