Granted Patent
B2
US 9,351,980 · App. 13/578,934 · Granted May 31, 2016
Di-aspirin derivatives
Assignee:
The University of Wolverhampton
A61K31/60A61K31/609A61K31/616A61K31/621C07C69/24C07C69/40C07C69/44C07C69/60C07C69/63C07C69/76C07C69/78C07C69/82C07C69/96C07C205/43C07C235/60C07C235/88
View Patent ↗
Loading inventors, assignments & file history…
Abstract
The invention relates to the use of di-aspirin (bis(2-carboxyphenyl)succinate) and its derivatives in the treatment of colon and colorectal cancer. It also relates to novel derivatives of di-aspirin and to a method of synthesis of the di-aspirin and its derivatives.
Claims (3)
1. A method of treating colorectal cancer, comprising administering an effective amount of a compound of Formula (III) or a pharmaceutically acceptable salt, solvate or hydrate thereof, to a patient in need thereof:
wherein Z is selected from trans —CH═CH— or —CH 2 CH 2 —.
2. The method of claim 1 , wherein Z is trans —CH═CH—.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 26, 2012
From: PERRY, CHRISTOPHER JOHN; NICHOLL, IAIN DOUGLAS
To: THE UNIVERISTY OF WOLVERHAMPTON
Reel/Frame 029198/0139 →
Priority Claims (1)
GB 10025302
· Feb 15, 2010
· national
Continuity (1)