IP Library Granted Patent US 9,370,449
Granted Patent B2
US 9,370,449 · App. 14/632,161 · Granted Jun 21, 2016

Phototherapy dressing for treating psoriasis

Inventors: Evan Anderson (Redwood City, CA); Christopher Pell (San Francisco, CA); Stephen Dugan (San Francisco, CA); Adam Martos (Santa Cruz, CA)
Assignee: Luma Therapeutics, Inc.
A61F13/00063A61F13/0213A61N5/0616A61K35/04A61L26/0066A61N2005/0645A61N2005/0661
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Quick Facts
Patent No.
US 9,370,449
App. No.
14/632,161
Granted
Jun 21, 2016
Kind
B2
Abstract

Methods and apparatuses for phototherapy to treat skin disorders. In particular, described herein are phototherapy dressings for use with phototherapy UV light applicators (sources) to treat skin disorders such as psoriasis. The dressings described herein may include a support body onto which a medicament formed of a hydrogel and coal tar and/or coal tar extract is held. The dressing may be configured so that at least half (50%) of the UV light within a therapeutic range of wavelengths is through the dressing including the medicament to the patient's skin. The dressings may be adapted for use in conjunction with a phototherapy UV light sources.

Claims (44)

1. A phototherapy dressing for treating psoriasis, the dressing comprising:

a support body having an island region;

a medicament in communication with the island region, the medicament comprising a hydrogel including a suspension of between 0.1% and 5% (by weight/volume) coal tar or coal tar extract mixed in the hydrogel, wherein the hydrogel comprises greater than 90% water and is between 0.005 to 0.1 inches thick;

wherein the medicament and island region together occlude less than 50% of UV light at wavelengths between 300 and 320 nm from passing through the phototherapy dressing; and

a magnetic attachment for a phototherapy UV light source on the support body, the magnetic attachment configured to secure the phototherapy UV light source over the island region of the phototherapy dressing.

2. The phototherapy dressing of claim 1 , further comprising an adhesive on the phototherapy dressing peripheral to the island region.

3. The phototherapy dressing of claim 1 , wherein the phototherapy dressing has a moisture vapor transmission of less than 2.3 g/m 2 /h.

4. The phototherapy dressing of claim 1 , wherein the support body comprises polyurethane.

5. The phototherapy dressing of claim 1 , wherein the support body comprises a thin layer of polymeric material having a thickness of less than 0.005 inches.

6. The phototherapy dressing of claim 1 , wherein the hydrogel is between 0.01 inches to 0.08 inches thick.

7. The phototherapy dressing of claim 1 , wherein the phototherapy dressing has a thickness of less than 0.5 cm.

8. The phototherapy dressing of claim 1 , wherein the medicament is layered onto the support body.

9. The phototherapy dressing of claim 1 , wherein the island region comprises a roughened surface region on the support body.

10. The phototherapy dressing of claim 1 , wherein the phototherapy dressing has a thermal conductivity of less than 0.32 W/m/° C.

11. The phototherapy dressing of claim 1 , further comprising a unique identifier associated with the phototherapy dressing.

12. The phototherapy dressing of claim 1 , further comprising a unique identifier associated with the phototherapy dressing, wherein the unique identifier is one of: an RFID tag, an optical code, a magnetic signature, or an alphanumeric code.

13. The phototherapy dressing of claim 1 , wherein the hydrogel comprises greater than 95% water.

14. The phototherapy dressing of claim 1 , wherein the magnetic attachment comprises a plurality of magnets on the support body.

15. A phototherapy dressing for treating psoriasis, the dressing comprising:

a support body;

a medicament in communication with the support body, the medicament comprising a hydrogel including a suspension of between 0.1% and 5% (by weight/volume) coal tar or coal tar extract mixed in the hydrogel, wherein the hydrogel comprises greater than 90% water and is between 0.005 to 0.1 inches thick;

wherein the medicament and support body together occlude less than 50% of UV light at wavelengths between 300 and 320 nm from passing through the phototherapy dressing;

an adhesive on the phototherapy dressing; and

a magnetic attachment for a phototherapy UV light source on the support body, the magnetic attachment configured to secure the phototherapy UV light source to the phototherapy dressing.

16. The phototherapy dressing of claim 15 , wherein the support body forms an island region in which the medicament is positioned, and the adhesive is located peripheral to the island region on the phototherapy dressing.

17. The phototherapy dressing of claim 15 , wherein the phototherapy dressing has a moisture vapor transmission of less than 2.3 g/m 2 /h.

18. The phototherapy dressing of claim 15 , wherein the support body comprises polyurethane.

19. The phototherapy dressing of claim 15 , wherein the support body comprises a thin layer of polymeric material having a thickness of less than 0.005 inches.

20. The phototherapy dressing of claim 15 , wherein the phototherapy dressing has a thickness of less than 0.5 cm.

21. The phototherapy dressing of claim 15 , wherein the hydrogel is between 0.01 inches to 0.08 inches thick.

22. The phototherapy dressing of claim 15 , wherein the medicament is layered onto the support body.

23. The phototherapy dressing of claim 15 , wherein the medicament is positioned within an island region comprising a roughened surface region on the support body.

24. The phototherapy dressing of claim 15 , wherein the phototherapy dressing has a thermal conductivity of less than 0.32 W/m/° C.

25. The phototherapy dressing of claim 15 , further comprising a unique identifier associated with the phototherapy dressing.

26. The phototherapy dressing of claim 15 , further comprising a unique identifier associated with the phototherapy dressing, wherein the unique identifier is one of: an RFID tag, an optical code, a magnetic signature, or an alphanumeric code.

27. The phototherapy dressing of claim 15 , wherein the hydrogel comprises greater than 95% water.

28. The phototherapy dressing of claim 15 , wherein the magnetic attachment comprises a plurality of magnets on the support body.

29. A phototherapy dressing for treating psoriasis, the dressing comprising:

a support body;

a medicament in communication with the support body, the medicament comprising a hydrogel including a suspension of between 0.1% and 5% (by weight/volume) coal tar or car tar extract mixed in the hydrogel, wherein the hydrogel comprises greater than 90% water and is between 0.005 to 0.1 inches thick;

wherein the medicament and support body together occlude less than 50% of UV light at wavelengths between 300 and 320 nm from passing through the phototherapy dressing;

an adhesive on the phototherapy dressing;

a unique identifier on the support body associated with the phototherapy dressing; and

a magnetic attachment for a phototherapy UV light source on the support body, the magnetic attachment configured to secure the phototherapy UV light source to the phototherapy dressing.

Assignments (2)
CHANGE OF NAME Recorded Feb 11, 2016
From: ILLUMICURE INC.
To: LUMA THERAPEUTICS, INC.
Reel/Frame 037717/0629 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 19, 2015
From: ANDERSON, EVAN; PELL, CHRISTOPHER; DUGAN, STEPHEN; MARTOS, ADAM
To: ILLUMICURE INC.
Reel/Frame 035206/0439 →
Continuity (3)
Provisional Application 61944755 · Feb 26, 2014
Provisional Application 62049366 · Sep 12, 2014
Related Publication 20150238774A1 · Aug 27, 2015