IP Library › Granted Patent US 9,376,400
Granted Patent B2
US 9,376,400 · App. 14/325,248 · Granted Jun 28, 2016

Process for the synthesis of triazoles

Inventors: Shili Chen (Cheshire, CT); Rongliang Lou (Cheshire, CT); Yusheng Wu (New Haven, CT); Jiacheng Zhou (Newark, DE); Roger Hanselmann (Branford, CT)
Assignee: MELINTA THERAPEUTICS, INC.
C07D249/04C07D413/06C07D413/12C07D413/14C07F7/0814
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Quick Facts
Patent No.
US 9,376,400
App. No.
14/325,248
Granted
Jun 28, 2016
Kind
B2
Abstract

The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

Claims (3)

1. A compound corresponding to the structure

or a pharmaceutically acceptable salt thereof, wherein each R 20 is independently C 1 -C 6 alkyl or —O—(C 1 -C 6 alkyl).

2. A compound according to claim 1 , wherein each R 20 is methyl.

Assignments (7)
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT (PATENTS) AT REEL 054836 AND FRAME 0824, REEL 061314 AND FRAME 0572 AND REEL 068260 AND FRAME 0283 Recorded Aug 29, 2025
From: SILICON VALLEY BANK, A DIVISION OF FIRST-CITIZENS BANK & TRUST COMPANY
To: MELINTA SUBSIDIARY CORP.
Reel/Frame 074576/0471 →
AMENDED AND RESTATED INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Aug 25, 2022
From: MELINTA SUBSIDIARY CORP.
To: SILICON VALLEY BANK
Reel/Frame 061314/0572 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Dec 22, 2020
From: MELINTA SUBSIDIARY CORP.
To: SILICON VALLEY BANK
Reel/Frame 054836/0824 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2019
From: MELINTA THERAPEUTICS, INC.
To: MELINTA SUBSIDIARY CORP.
Reel/Frame 048030/0489 →
SECURITY INTEREST Recorded Jan 8, 2018
From: MELINTA THERAPEUTICS, INC.; REMPEX PHARMACEUTICALS, INC.; CEMPRA PHARMACEUTICALS, INC.; CEM-102 PHARMACEUTICALS, INC.
To: CORTLAND CAPITAL MARKET SERVICES LLC, AS AGENT
Reel/Frame 045019/0552 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 19, 2016
From: CHEN, SHILI; LOU, ROBGLIANG; WU, YUSHENG; ZHOU, JIACHENG; HANSELMANN, ROGER
To: RIB-X PHARMACEUTICALS, INC.
Reel/Frame 038643/0448 →
CHANGE OF NAME Recorded May 19, 2016
From: RIB-X PHARMACEUTICALS, INC.
To: MELINTA THERAPEUTICS, INC.
Reel/Frame 038754/0970 →
Continuity (4)
Continuation 13845759 · Mar 18, 2013
Continuation 11921838
Provisional Application 60688990 · Jun 8, 2005
Related Publication 20150158827A1 · Jun 11, 2015