Tissue cassette with biasing element

1. An apparatus for holding a tissue sample comprising,

a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and

a base comprising a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other,

wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area,

wherein the biasing element is substantially hinged,

wherein the biasing element comprises:

a first member connected at a first end to the first tissue engaging surface and that extends substantially parallel to the first tissue engaging surface;

a first angled member which extends downward from a second end of the first member;

a second angled member connected to the first angle member extending upward, wherein the second angled member and the first angled member form an angle less than 90°;

a third angle member connected to the second angled member extending downward, wherein the third angled member and the second angled member form an angle less than 90°; and

a second member connected to the third angle member and that extends substantially parallel to the first tissue engaging surface.

2. An apparatus for holding a tissue sample comprising,

a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and

a base comprising a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other,

wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area,

wherein the retaining member comprises two biasing elements for moveably supporting the first tissue engaging surface such that the first tissue engaging surface is urged toward the second tissue engaging surface,

wherein the retaining member comprises a rim portion and a tissue retaining element on which the first tissue engaging surface is defined, and

wherein the tissue retaining element is connected to the rim portion by the biasing elements.

3. The apparatus according to claim 2 , wherein the tissue retaining element includes a connecting portion to which the biasing elements are respectively connected.

4. The apparatus according to claim 2 , wherein the tissue retaining element has a basket-shape with four side walls and a bottom surface.

5. An apparatus for holding a tissue sample comprising,

a retaining member having a first tissue engaging surface;

a base having a second tissue engaging surface; and

at least one biasing element,

wherein at least one of the first tissue engaging surface and the second tissue engaging surface is moveably attached to at least one of the retaining member and the base by said biasing element,

wherein the base and the retaining member are configured to engage each other to form an interior area with the first and second tissue engaging surfaces facing each other, and

wherein the at least one biasing element urges at least one of the first tissue engaging surface and the second tissue engaging surface to retain the tissue sample there between in the interior area,

wherein the retaining member has at least two biasing elements,

wherein the at least two biasing elements urge the first engaging surface of the retaining member toward the second engaging surface of the base and maintain the engaging surfaces in a substantially parallel configuration,

wherein the biasing element comprises:

a pair of angled members, each having a first end and a second end,

wherein each angled members being connected at its first end to the retaining member,

wherein the pair of angled members extend in opposite directions to form a crossed configuration, and

wherein the pair of angled members are each connected at its second end to opposite ends of the retaining element by a flexing portion to allow the pair of angled members to flex under pressure.