Variable zone high metal to vessel ratio stent and method
A variable zone high metal to vessel ratio stent includes a proximal high metal to vessel ratio zone, a central low metal to vessel ratio zone, and a distal high metal to vessel ratio zone. The proximal high metal to vessel ratio zone is deployed with fixation and sealing to healthy tissue of a main vessel superior to branch vessels and an aneurysm. The central low metal to vessel ratio zone is deployed directly on ostai of the branch vessels. However, as the central low metal to vessel ratio zone is highly permeable, blood flows from the main vessel through the central low metal to vessel ratio zone and into branch vessels.
1. A prosthesis comprising:
a first high metal to vessel ratio zone having first serpentine rings and defining a high metal to vessel ratio within a range of 30 percent to 80 percent, the first high metal to vessel ratio zone located at a first end of the prosthesis;
a second low metal to vessel ratio zone having second serpentine rings and defining a low metal to vessel ratio less than 30 percent; and
a third high metal to vessel ratio zone having third serpentine rings and defining a high metal to vessel ratio within the range of 30 percent to 80 percent, the third high metal to vessel ratio zone located at a second end of the prosthesis;
wherein the first high metal to vessel ratio zone, the second low metal to vessel ratio zone, and the third high metal to vessel ratio zone are integral, and wherein the second low metal to vessel ratio zone is located between the first high metal to vessel ratio zone and the third high metal to vessel ratio zone.
2. The prosthesis of claim 1 wherein the second serpentine rings are larger than the first serpentine rings.
3. The prosthesis of claim 2 wherein the first serpentine rings have a first wavelength and a first amplitude, and the second serpentine rings have a second wavelength and a second amplitude, the second wavelength being greater than the first wavelength, and the second amplitude is greater than the first amplitude.
4. The prosthesis of claim 3 wherein the third serpentine rings are smaller than the second serpentine rings.
5. The prosthesis of claim 4 wherein the third serpentine rings have a third wavelength and a third amplitude, the second wavelength being greater than the third wavelength, and the second amplitude is greater than the third amplitude.
6. The prosthesis of claim 4 further comprising connector bars connecting the first, second, and third serpentine rings together.
7. The prosthesis of claim 4 wherein the first, second, and third serpentine rings comprise proximal apexes, distal apexes, and struts connecting the proximal apexes and the distal apexes.
8. The prosthesis of claim 1 wherein the first high metal to vessel ratio is within the range of 35 percent to 60 percent.
9. The prosthesis of claim 1 further comprising:
a surface treatment to encourage tissue ingrowth.
10. The prosthesis of claim 9 wherein the surface treatment comprises a metal.
11. The prosthesis of claim 9 wherein the surface treatment comprises roughening the prosthesis.
12. The prosthesis of claim 9 wherein the surface treatment comprises a growth factor.
13. A delivery system comprising: a prosthesis comprising:
a first high metal to vessel ratio zone having first serpentine rings and defining a high metal to vessel ratio within a range of 30 percent to 80 percent, the first high metal to vessel ratio zone located at a first end of the prosthesis;
a second low metal to vessel ratio zone having second serpentine rings and defining a low metal to vessel ratio less than 30 percent;
a third high metal to vessel ratio zone having third serpentine rings and defining a high metal to vessel ratio within the range of 30 percent to 80 percent, the third high metal to vessel ratio zone located at a second end of the prosthesis;
wherein the first high metal to vessel ratio zone, the second low metal to vessel ratio zone, and the third high metal to vessel ratio zone are integral, and wherein the second low metal to vessel ratio zone is located between the first high metal to vessel ratio zone and the third high metal to vessel ratio zone; and
an outer sheath radially constraining the prosthesis.
14. The delivery system of claim 13 further comprising an inner member, the prosthesis being radially constrained around the inner member by the outer sheath.