IP Library Granted Patent US 9,409,862
Granted Patent B2
US 9,409,862 · App. 14/084,131 · Granted Aug 9, 2016

Compositions for preventing and/or treating degenerative disorders of the central nervous system

Inventors: Robert Boyd (Horsham, PA); Gary Lee (West Windsor, NJ); Philip Rybczynski (Branchburg, NJ)
Assignee: Amicus Therapeutics, Inc.
C07D211/46A61K31/191A61K31/445A61K45/06C07D211/44C07D211/60C07D211/96
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Quick Facts
Patent No.
US 9,409,862
App. No.
14/084,131
Granted
Aug 9, 2016
Kind
B2
Abstract

The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease.

Claims (15)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt, or solvate thereof.

2. A compound represented by the formula:

or a pharmaceutically acceptable salt thereof.

3. A compound represented by the formula:

or a pharmaceutically acceptable salt thereof.

4. A compound represented by the formula:

or a pharmaceutically acceptable salt thereof.

5. A compound represented by the formula:

or a pharmaceutically acceptable salt thereof.

6. A pharmaceutical composition comprising at least one compound of claim 1 and at least one pharmaceutically acceptable carrier.

7. The compound of claim 1 , which is represented by the formula:

or a pharmaceutically acceptable salt thereof.

8. The pharmaceutical composition of claim 6 , wherein the compound is represented by the formula:

or a pharmaceutically acceptable salt thereof.

Assignments (2)
SECURITY INTEREST Recorded Apr 27, 2026
From: BIOMARIN PHARMACEUTICAL INC.; AMICUS THERAPEUTICS, INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 075493/0968 →
SECURITY INTEREST Recorded Oct 6, 2023
From: AMICUS THERAPEUTICS, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 065177/0196 →
Continuity (3)
Continuation 12898112 · Oct 5, 2010
Provisional Application 61252803 · Oct 19, 2009
Related Publication 20140080871A1 · Mar 20, 2014