IP Library Granted Patent US 9,416,161
Granted Patent B2
US 9,416,161 · App. 14/163,755 · Granted Aug 16, 2016

Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof

Inventor: Ira M. Herman (Newton, MA)
Assignee: TRUSTEES OF TUFTS COLLEGE
C07K14/435C07K7/06C07K7/08C07K14/47C12N15/113A61K38/00C12N2310/11C12N2320/30
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Quick Facts
Patent No.
US 9,416,161
App. No.
14/163,755
Granted
Aug 16, 2016
Kind
B2
Abstract

The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like.

Claims (3)

1. A peptide comprising an amino acid sequence that is not less than 95% identical to the amino acid sequence of SEQ ID NO: 3.

2. A composition comprising the peptide of claim 1 and a pharmaceutically acceptable carrier.

3. A polynucleotide that encodes the peptide of claim 1 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 30, 2014
From: HERMAN, IRA M.
To: TRUSTEES OF TUFTS COLLEGE
Reel/Frame 032089/0048 →
Continuity (5)
Continuation 13919370 · Jun 17, 2013
Continuation 13126145
Provisional Application 61197420 · Oct 27, 2008
Related Publication 20140371154A1 · Dec 18, 2014
Related Publication 20150353612A9 · Dec 10, 2015