Skin properties improving agent for oral administration
Disclosed is a skin property-improving agent which exerts excellent effects by oral administration. The skin property-improving agent for oral administration contains, as an active ingredient, a bacterium belonging to the genus Streptococcus and a bacterium belonging to the genus Bifidobacterium , or fermented milk containing the two bacteria.
1. A method for treating skin damage arising from ultraviolet radiation in a subject in need thereof, the method consisting of orally ingesting a composition consisting of, as an active ingredient, (i) a bacterium of genus Streptococcus and a bacterium of genus Bifidobacterium , (ii) fermented milk consisting of the two bacteria;
wherein each of the bacteria are present in the composition in an amount of about 10 3 to 10 13 CFU, and are (A) the bacterium of-genus Streptococcus is Streptococcus thermophilus YIT 2021 (FERM BP-7537); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 12272 (FERM BP-11320);
(B) the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2084 (FERM BP-10879); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 12272 (FERM BP-11320);
(C) the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2084 (FERM BP-10879); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 4065 (FERM BP-8223); or
(D) the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2021 (FERM BP-7537); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 4065 (FERM BP-6223).
2. The method of claim 1 , further comprising orally ingesting galacto-oligosaccharide.
3. The method of claim 1 , wherein the composition inhibits a reduction in water content of stratum corneum caused by ultraviolet irradiation.
4. The method of claim 1 , wherein the composition promotes an increase in water content of stratum corneum.
5. The method of claim 1 , wherein the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2021 (FERM BP-7537) and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 12272 (FERM BP-1 1320).
6. The method of claim 1 , wherein the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2084 (FERM BP-10879); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 12272 (FERM BP-11320).
7. The method of claim 1 , wherein the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2084 (FERM BP-10879); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 4065 (FERM BP-6223).
8. The method of claim 1 , wherein the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2021 (FERM BP-7537) and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 4065 (FERM BP-6223).
9. The method of claim 1 , wherein each of the bacteria are present in the composition in an amount of about 10 6 to 10 13 CPU.
10. The method of claim 1 , wherein each of the bacteria are present in the composition in an amount of about 10 7 to 10 13 CFU.
11. The method of claim 1 , wherein each of the bacteria are present in the composition in an amount of about 10 8 to 10 13 CPU.
12. The method of claim 1 , wherein each of the bacteria are present in the composition in an amount of about 10 3 to 10 8 CFU.
13. A method for treating skin damage arising from ultraviolet radiation selected from the group consisting of inflammation, immune suppression, or DNA damage in a subject in need thereof, the method consisting of orally ingesting a composition consisting of, as an active ingredient, (i) a bacterium of genus Streptococcus and a bacterium of genus Bifidobacterium , or (ii) fermented milk comprising the two bacteria;
wherein each of the bacteria are present in the composition in an amount of about 10 3 to 10 13 CFU, and are (A) the bacterium of-genus Streptococcus is Streptococcus thermophilus YIT 2021 (FERM BP-7537); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 12272 (FERM BP-11320);
(B) the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2084 (FERM BP-10879); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 12272 (FERM BP-11320);
(C) the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2034 (FERM BP-10879); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 4065 (FERM BP-6223); or
(D) the bacterium of genus Streptococcus is Streptococcus thermophilus YIT 2021 (FERM BP-7537); and the bacterium of genus Bifidobacterium is Bifidobacterium breve YIT 4065 (FERM BP-6223).