Hydrophilic adhesives and tapes and devices containing the same
Hydrophilic adhesive compositions are disclosed that contain a surfactant that is miscible, but not fully soluble in the polymer matrix of the adhesive. This permits the surfactant to continuously replenish at the surface of the adhesive as other surfactant is removed, such as when it is carried away by an aqueous sample flowing over that surface in an in-vitro diagnostic device, resulting in adhesive compositions that are inherently hydrophilic on their surfaces and do not rely on the bloom mechanism of known hydrophilic adhesives. This provides greater design options for in-vitro diagnostic device manufacturers, including the use of hydrophilic adhesive spacers in lieu of or in combination with hydrophilic top covers.
1. A composition comprising a hydrophobic polymer matrix and a surfactant, wherein the surfactant is miscible but not fully soluble in the polymer matrix, wherein the composition is a hydrophilic pressure sensitive or a hydrophilic heat activated adhesive and wherein the polymer matrix comprises methoxyethyl acrylate.
2. The composition of claim 1 , wherein the composition is a hydrophilic pressure sensitive adhesive.
3. The composition of claim 1 , wherein the composition is a hydrophilic heat activated adhesive.
4. The composition of claim 1 , wherein the surfactant is a non-ionic surfactant.
5. The composition of claim 4 , wherein the surfactant is ethoxylated polydimethylsiloxane.
6. The composition of claim 1 , wherein the surfactant to polymer matrix ratio on a solids weight basis is in the range of 1:99 to 10:90.
7. The composition of claim 6 , wherein the surfactant is present in the range of 3% to 6% by weight, on a solids basis, of the polymer matrix.
8. A composition comprising a hydrophobic acrylic co-polymer matrix and a surfactant, wherein the surfactant is ethoxylated polydimethylsiloxane, the ethoxylated polydimethylsiloxane being miscible but not fully soluble in the acrylic co-polymer, wherein the relative weight percentages of acrylic co-polymer to ethoxylated polydimethylsiloxane on a solids basis is 95% by weight acrylic co-polymer and 5% by weight ethoxylated polydimethylsiloxane, wherein the composition is formulated as a hydrophilic pressure sensitive or a hydrophilic heat activated adhesive and wherein the acrylic co-polymer matrix is a co-polymer comprising methoxyethyl acrylate.
9. The composition of claim 8 , wherein the acrylic co-polymer matrix is a co-polymer of 50% methoxyethyl acrylate, 18.5% methyl acrylate, 18.5% ethyl acrylate, 10% butyl acrylate, and 3% HEA, all by weight.
10. The composition of claim 8 , wherein the acrylic co-polymer matrix is a co-polymer of 53% methoxyethyl acrylate, 23% methyl methacrylate, 23% methyl acrylate, 1.2% acrylic acid, all by weight.
11. The composition of claim 8 , wherein the acrylic co-polymer matrix is a co-polymer of 52% methoxyethyl acrylate, 18.5% methyl acrylate, 18.5% ethyl acrylate, 10% butyl acrylate, and 1% acrylic acid.
12. A tape comprising a layer of the composition of claim 1 , wherein the tape exhibits surfactant replenishment at a surface of the layer.
13. The tape of claim 12 , wherein the layer of the composition is supported on a carrier layer.
14. The tape of claim 13 , further comprising a release liner on a side of the composition layer opposite the carrier layer.
15. The tape of claim 12 , wherein the layer of the composition is a self-supporting hydrophilic heat activated adhesive film.
16. A diagnostic device comprising a fluid flow path, wherein the composition of claim 1 forms a portion of the fluid flow path.
17. The diagnostic device of claim 16 , wherein the fluid flow path is an elongated channel formed by a base, a top cover, and a spacer defining opposite sides of the channel.
18. The diagnostic device of claim 17 , wherein the spacer comprises the composition.
19. The diagnostic device of claim 17 , wherein the top cover comprises the composition.
20. The diagnostic device of claim 16 , wherein the device is a microfluidic or lateral flow device.