Methods and systems for incorporating nicotine into oral products
This document provides methods and systems for stabilizing nicotine and incorporating nicotine into one or more oral products. This document also provides oral products. Nicotine can be stabilized by mixing liquid nicotine with cellulosic fiber such that the liquid nicotine absorbs into pores of the cellulosic fiber to form a cellulosic fiber-nicotine mixture. In some cases, a cellulosic fiber-nicotine mixture can be combined with one or more binders and molded into an oral product.
1. A method for stabilizing nicotine, comprising
mixing liquid nicotine with cellulosic fiber such that the liquid nicotine absorbs into pores of the cellulosic fiber to form a cellulosic fiber-nicotine mixture; and
loosely depositing the cellulosic fiber-nicotine mixture within a container,
wherein the cellulosic fiber comprises wood pulp, cotton, sugar beets, bran, citrus pulp fiber, switch grass and other grasses, Salix , tea, Populus , bamboo fibers, or combinations thereof.
2. The method of claim 1 , wherein the liquid nicotine comprises at least 1 weight percent nicotine.
3. The method of claim 2 , wherein the liquid nicotine comprises between 2 weight percent and 75 weight percent nicotine and at least one diluent.
4. The method of claim 3 , wherein the at least one diluent is selected from the group consisting of plasticizers, humectants, flavorants, or a combination thereof.
5. The method of claim 1 , further comprising diluting the liquid nicotine with a diluent prior to mixing the liquid nicotine with cellulosic fibers.
6. The method of claim 1 , further comprising allowing the cellulosic fiber-nicotine mixture to equilibrate within a sealed container for at least 1 hour.
7. The method of claim 1 , wherein the cellulosic fiber comprises pores having an average pore size of between about 3 nanometers and about 300 nanometers.
8. A method for incorporating liquid nicotine into an oral product, comprising:
(a) mixing liquid nicotine with cellulosic fiber to produce a cellulosic fiber-nicotine mixture, wherein the cellulosic fiber comprises wood pulp, cotton, sugar beets, bran, citrus pulp fiber, switch grass and other grasses, Salix , tea, Populus , bamboo fibers, or combinations thereof;
(b) mixing the cellulosic fiber-nicotine mixture with one or more binders to form an oral product pre-molding mixture, the one or more binders comprising a chewing gum base; and
(c) molding the oral product pre-molding mixture into an oral product.
9. The method of claim 8 , further comprising diluting the liquid nicotine with one or more diluents prior to mixing the liquid nicotine with the cellulosic fiber to form the cellulosic fiber-nicotine mixture.
10. The method of claim 9 , wherein the one or more diluents comprise a plasticizer, a flavorant, a humectant, or a combination thereof.
11. The method of claim 9 , wherein the one or more diluents comprise propylene glycol and the liquid nicotine is diluted to a concentration of between 5% and 25% weight percent nicotine prior to mixing the liquid nicotine with the cellulosic fiber to form the cellulosic fiber-nicotine mixture.
12. The method of claim 8 , wherein the ratio of liquid nicotine to cellulosic fiber by weight is between 1/1000 and 50/50.
13. The method of claim 8 , further comprising holding the cellulosic fiber-nicotine mixture in a sealed container for at least an hour such that the cellulosic fiber-nicotine mixture equilibrates prior to mixing the cellulosic fiber-nicotine mixture with the binder.
14. The method of claim 8 , wherein the binder is a chewing gum base.
15. The method of claim 8 , wherein the binder is selected from the group consisting of dextrin or dextrin derivative, carboxymethyl cellulose, hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, methyl cellulose, starch, konjac, collagen, inulin, soy protein, whey protein, casein, wheat gluten, carrageenan, alginates, propylene glycol alginate, xanthan, dextrin, pullulan, curdlan, gellan, locust bean gum, guar gum, tara gum, gum tragacanth, pectin, agar, zein, karaya, gelatin, psyllium seed, chitin, chitosan, gum acacia, polyvinyl pyrrolidone, polyethylene oxide, polyvinyl alcohol, guar gum, xanthan, cellulose, maltodextrin or other modified starch, polyurethane, silicon polymer, polyester, polyacrylate, polyethylene, poly(styrene-ethylene-butylene-styrene) (“SEBS”), poly(styrene-butadiene-styrene) (“SBS”), poly(styrene-isoprene-styrene)(“SIS”), couma macrocarpa, loquat, tunu, jelutong, chicle, styrene-butadiene rubber, butyl rubber, and polyisobutylene, glycerol esters of gum, terpene resins, polyvinyl acetate, paraffin, microcrystalline wax, hydrogenated vegetable oils, lecithin, glycerol monosterate, natural latexes, chicle, spruce gum, mastic gum, or a combination thereof.
16. The method of claim 8 , wherein molding the oral product pre-molding mixture into the oral product comprises compression molding the oral product pre-molding mixture into a predetermined shape.
17. The method of claim 8 , wherein the oral product pre-molding mixture comprises a dry mixture of ingredients.
18. The method of claim 8 , wherein the oral product pre-molding mixture is substantially free of ion-exchange resins.
19. The method of claim 8 , wherein the oral product pre-molding mixture is substantially free of buffering agents.