Carriers for hemostatic tract treatment

1. An apparatus for administration of at least one hemostatic agent to a tissue surrounding an opening in a wall of a body lumen, the apparatus comprising:

an elongate element that includes a proximal end, an open distal end, a lumen extending therebetween, and an outer surface having a tissue contacting region and a body lumen-penetrating region; and

at least one hemostatic agent disposed on the tissue-contacting region, and

a depth indicia configured to designate the tissue-contacting region, the depth indicia includes a first color on the tissue-contacting region and a second color on the body lumen-penetrating region.

2. The apparatus as recited in claim 1 , wherein the tissue-contacting region includes at least a portion of the elongate element that is capable of contacting non-vascular tissues surrounding a venous or arterial puncture site without being inserted into or contacting an inside portion of the vein or artery.

3. The apparatus as recited in claim 1 , the at least one hemostatic agent is included as a component of a coating over and/or a mixture with a material that defines the tissue-contacting region.

4. An apparatus for administration of at least one hemostatic agent to a tissue surrounding an opening in a wall of a body lumen, the apparatus comprising:

an elongate element that includes a tissue-contacting region, a body lumen-penetrating region, a proximal end, a distal end, and a lumen extending therebetween;

at least one hemostatic agent disposed on the tissue-contacting region, the body lumen-penetrating region being substantially devoid of the hemostatic agent; and

a depth indicia positioned on the elongate element, the depth indicia being configured to designate the tissue-contacting region, wherein the depth indicia includes a first color on the tissue-contacting region and a second color on the body lumen-penetrating region.

5. The apparatus as recited in claim 4 , wherein the depth indicia includes at least one radiopaque band.

6. The apparatus as recited in claim 4 , wherein the body lumen-penetrating region includes at least a portion of the elongate, substantially cylindrical element that is capable of being inserted into or contacting an inside portion of a vein or artery.

7. The apparatus as recited in claim 6 , wherein the body lumen-penetrating region includes a length that is at least partially defined by a diameter of the inside portion of the vein or artery.

8. The apparatus as recited in claim 4 , wherein the at least one hemostatic agent is selected from a group consisting of aminocaproic acid, prothrombin, thrombin, thromboxane A2, thromboxane B2, an endothelin, a vasoconstrictor, an adrenergic agent, an angiotensin, lysine, polylysine, tranexamic acid, N-acetyl-lysine-methyl ester, bentonite, collagen, chitosan, cationic polymers, viscosity increasing polymers, anti-fibrinolytic proteins, coagulation catalyzing compounds, coagulation factors, or crosslinkers, derivatives thereof, pharmaceutically acceptable salts thereof, and combinations thereof.

9. An apparatus for administration of at least one hemostatic agent to a tissue surrounding an opening in a wall of a body lumen, the apparatus comprising:

an elongate element that includes a tissue-contacting region, a proximal end, a distal end, and a lumen extending therebetween;

a depth indicia positioned on the elongate element, the depth indicia being configured to designate the tissue-contacting region, the depth indicia includes a first color on the tissue-contacting region and a second color on the body lumen-penetrating region; and

at least one hemostatic agent disposed on the tissue-contacting region, the at least one hemostatic agent being selected from a group including aminocaproic acid, prothrombin, thrombin, thromboxane A2, thromboxane B2, an endothelin, a vasoconstrictor, an adrenergic agent, an angiotensin, lysine, polylysine, tranexamic acid, N-acetyl-lysine-methyl ester, bentonite, collagen, chitosan, cationic polymers, viscosity increasing polymers, anti-fibrinolytic proteins, coagulation catalyzing compounds, coagulation factors, or crosslinkers, derivatives thereof, pharmaceutically acceptable salts thereof, and combinations thereof.

10. The apparatus as recited in claim 9 , wherein the at least one hemostatic agent is included as a component of a coating over and/or a mixture with a material that defines the tissue-contacting region.

11. The apparatus as recited in claim 9 , wherein the body lumen-penetrating region is substantially devoid of hemostatic agent.

12. The apparatus as recited in claim 9 , wherein the depth indicia includes at least one radiopaque band.