IP Library Granted Patent US 9,545,227
Granted Patent B2
US 9,545,227 · App. 14/231,547 · Granted Jan 17, 2017

Sleep apnea syndrome (SAS) screening using wearable devices

Inventors: Nandakumar Selvaraj (Santa Clara, CA); Ravi Narasimhan (Sunnyvale, CA)
Assignee: VITAL CONNECT, INC.
A61B5/4818A61B5/0004A61B5/0006A61B5/0205A61B5/0402A61B5/04012A61B5/0456A61B5/11A61B5/1121A61B5/6801A61B5/6833A61B5/7267A61B5/0452A61B5/1116A61B5/7203
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Quick Facts
Patent No.
US 9,545,227
App. No.
14/231,547
Granted
Jan 17, 2017
Kind
B2
Abstract

A method and system for Sleep Apnea Syndrome (SAS) screening are disclosed. The method comprises detecting at least one physiological signal, converting the at least one physiological signal into at least one sensor stream, and processing the at least one sensor stream to perform the SAS screening. The system includes a sensor to detect at least one physiological signal, a processor coupled to the sensor, and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to convert the at least one physiological signal into at least one sensor stream and to processor the at least one sensor stream to perform the SAS screening.

Claims (27)

1. A method for Sleep Apnea Syndrome (SAS) screening, the method comprising:

detecting at least one physiological signal;

converting the at least one physiological signal into at least one sensor stream;

preprocessing the at least one sensor stream;

determining a feature vector using a combination of feature extraction on the at least one sensor stream and patient information; and

performing machine learning optimization using the feature vector to perform the SAS screening.

2. The method of claim 1 , wherein the detecting step is performed by a wearable device, further wherein the at least one physiological signal includes any of an ECG signal and an accelerometer signal.

3. The method of claim 2 , wherein the converting step is performed by an electronic module of the wearable device, further wherein the at least one sensor stream includes any of an RR interval, an amplitude of the QRS waveform (RWA), an area of the QRS waveform (RA), a MEMS derived respiration signal, a signal magnitude area (SMA) of an accelerometer signal, and a posture angle.

4. The method of claim 1 , wherein the processing step is performed by any of a wearable device, an external device, a relay/cloud processor, a smartphone device, and a cloud computing system.

5. The method of claim 1 , wherein the preprocessing step further comprises any of eliminating wearable device off instances, removing trends, detecting and removing outliers, detecting and removing artifacts, normalization of ECG derived respiration signals, and normalization of MEMS derived respiration signals.

6. The method of claim 1 , wherein the performing feature extraction step utilizes any of time-domain analysis, statistical analysis, nonlinear analysis, frequency-domain analysis, and posture analysis to extract features from the at least one preprocessed sensor stream.

7. The method of claim 1 , wherein the performing machine learning optimization step utilizes the feature vector and an optimized model to perform any of parameter optimization, feature selection, model optimization, and minimum misclassification error (MCE) determination.

8. The method of claim 1 , further comprising:

automatically screen SAS disorder using overnight based signal analysis that does not involve computation of apnea and hypopnea Index values.

9. A wearable device for Sleep Apnea Syndrome (SAS) screening, the wearable device comprising a sensor to detect at least one physiological signal, a processor coupled to the sensor, and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to:

convert the at least one physiological signal into at least one sensor stream;

preprocess the at least one sensor stream;

determine a feature vector using a combination of feature extraction on the at least one sensor stream and patient information; and

perform machine learning optimization using the feature vector to perform the SAS screening.

10. The wearable device of claim 9 , wherein the at least one physiological signal includes any of an ECG signal and an accelerometer signal.

11. The wearable device of claim 10 , wherein the at least one sensor stream includes any of an RR interval, an amplitude of the QRS waveform (RWA), an area of the QRS waveform (RA), a MEMS derived respiration signal, a signal magnitude area (SMA) of an accelerometer signal, and a posture angle.

12. The wearable device of claim 9 , wherein any of the preprocessing, feature extraction, and machine learning optimization is performed by a processor external to the wearable device, wherein the external processor includes any of an external device, a relay/cloud processor, a smartphone device, and a cloud computing system.

13. The wearable device of claim 9 , wherein the preprocessing further comprises any of eliminating wearable device off instances, removing trends, detecting and removing outliers, detecting and removing artifacts, normalization of ECG derived respiration signals, and normalization of MEMS derived respiration signals.

14. The wearable device of claim 9 , wherein the feature extraction utilizes any of time-domain analysis, statistical analysis, nonlinear analysis, frequency-domain analysis, and posture analysis to extract features from the at least one preprocessed sensor stream.

15. The wearable device of claim 9 , wherein the machine learning optimization utilizes the feature vector and an optimized model to perform any of parameter optimization, feature selection, model optimization, and minimum classification error (MCE) determination.

16. The wearable device of claim 9 , wherein the application, when executed by the processor, further causes the processor to:

automatically screen SAS disorder using overnight based signal analysis that does not involve computation of apnea and hypopnea Index values.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Jul 5, 2024
From: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
To: VITAL CONNECT, INC.
Reel/Frame 068146/0132 →
SECURITY INTEREST Recorded Jul 5, 2024
From: VITAL CONNECT, INC.
To: TRINITY CAPITAL INC.
Reel/Frame 068146/0160 →
SECURITY INTEREST Recorded Jan 8, 2021
From: VITAL CONNECT, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 054941/0651 →
RELEASE OF SECURITY INTEREST Recorded Jan 8, 2021
From: OXFORD FINANCE LLC
To: VITAL CONNECT, INC.
Reel/Frame 054941/0743 →
SECURITY INTEREST Recorded Apr 9, 2020
From: VITAL CONNECT, INC.
To: OXFORD FINANCE LLC
Reel/Frame 052354/0752 →
RELEASE OF SECURITY INTEREST Recorded Oct 5, 2017
From: PERCEPTIVE CREDIT OPPORTUNITIES FUND, L.P.; PERCEPTIVE CREDIT OPPORTUNITIES GP, LLC
To: VITAL CONNECT, INC.
Reel/Frame 043797/0083 →
PATENT SECURITY AGREEMENT Recorded Jun 10, 2016
From: VITAL CONNECT, INC.
To: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP; PERCEPTIVE CREDIT OPPORTUNITIES GP, LLC
Reel/Frame 039012/0547 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2014
From: SELVARAJ, NANDAKUMAR; NARASIMHAN, RAVI
To: VITAL CONNECT, INC.
Reel/Frame 032567/0533 →
Continuity (2)
Provisional Application 61916024 · Dec 13, 2013
Related Publication 20150164410A1 · Jun 18, 2015