IP Library Granted Patent US 9,737,434
Granted Patent B2
US 9,737,434 · App. 13/888,168 · Granted Aug 22, 2017

Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells

Inventor: John W. Allison (Los Altos, CA)
Assignee: Zeltiq Aestehtics, Inc.
A61F7/0085A61F7/10A61B2017/00106A61F2007/0075A61F2007/0095A61F2007/029A61F2007/0296
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Quick Facts
Patent No.
US 9,737,434
App. No.
13/888,168
Granted
Aug 22, 2017
Kind
B2
Abstract

Systems for removing heat from a subject's subcutaneous lipid-rich regions, such as tissue, organs, cells, and so forth, are described herein. In various embodiments, the system includes a treatment device and a controller for controlling a treatment process. The controller is configured to detect and compensate for an interruption in the treatment process.

Claims (72)

1. A method for treating a subcutaneous lipid-rich region of a subject having skin, comprising:

heating or cooling the subcutaneous lipid-rich region of the subject according to a profile of a treatment process, the profile having a total duration;

identifying an interruption in the treatment process after a first duration,

determining a second duration of the identified interruption;

determining a third duration equal to a difference between the total duration and the first duration;

compensating for (1) rewarming of the subcutaneous lipid-rich region of the subject during the second duration when the subcutaneous lipid-rich region is cooled during the first duration and (2) a temperature decrease in the subcutaneous lipid-rich region when the subcutaneous lipid-rich region is heated during the first duration; and

after compensating for rewarming of the subcutaneous lipid-rich region or the temperature decrease in the subcutaneous lipid-rich region, continuing the treatment process according to the profile for the third duration.

2. The method of claim 1 , further comprising determining an interruption temperature (T interrupt ) of the subcutaneous lipid-rich region after the first duration and a rewarming temperature (T rewarm ) of the subcutaneous lipid-rich region after the second duration based on the first and second durations, respectively.

3. The method of claim 1 , further comprising determining an interruption temperature (T interrupt ) of the subcutaneous lipid-rich region after the first duration and a rewarming temperature (T rewarm ) of the subcutaneous lipid-rich region after the second duration based on the first and second durations, respectively, wherein the profile is a first profile, and wherein the method further includes determining a second profile having a cooling rate ({dot over (Q)}) calculated as follows:

Q

.

=

ρ

VC

p

(

T

rewarm

-

T

interrupt

)

π

where ρ is a density, V is a volume, and C p is a specific heat capacity of the subcutaneous lipid-rich region; and π is a recovery duration.

4. The method of claim 1 , further comprising determining an interruption temperature (T interrupt ) of the subcutaneous lipid-rich region after the first duration and a rewarming temperature (T rewarm ) of the subcutaneous lipid-rich region after the second duration based on the first and second durations, respectively, wherein the profile is a first profile, and wherein the method further includes determining a second profile having an expected rate of change for a temperature at the skin of the subject as follows:

Δ

T

=

(

T

rewarm

-

T

interrupt

)

π

where π is a recovery duration.

5. The method of claim 4 wherein compensating for rewarming includes

monitoring a rate of change for the temperature at the skin of the subject; and

adjusting the second profile for the recovery process if the monitored rate of change deviates from the expected rate of change by a preselected amount.

6. The method of claim 4 wherein compensating for rewarming includes

monitoring a rate of change for the temperature at the skin of the subject; and

adjusting the second profile for the recovery process if the monitored rate of change deviates from the expected rate of change by a preselected percentage.

7. The method of claim 1 , further comprising:

determining a compensation cooling/heating rate based on the second duration; and

cooling or heating the subcutaneous lipid-rich region based on the compensation cooling/heating rate to compensate for the rewarming or the temperature decrease of the subcutaneous lipid-rich cells.

8. The method of claim 1 , further comprising:

determining whether to resume the treatment process after the identified interruption based on the second duration and/or a number of interruption occurrences;

if the determination is to resume the treatment process, the treatment process is continued according to the profile for the third duration; and

if the determination is to not resume the treatment process, the treatment process according to the profile is stopped.

9. A computer-readable medium containing instructions for performing the method of claim 1 .

10. A method for treating a subcutaneous lipid-rich region of a subject having skin, comprising:

heating or cooling the subcutaneous lipid-rich region of the subject according to a profile of a treatment process, the profile having a total duration;

identifying an interruption in the treatment process after a first duration,

determining an interrupt duration of the interruption;

determining a compensation treatment profile based on the interrupt duration, the compensation treatment profile being different from the profile of the treatment process;

heating or cooling the subcutaneous lipid-rich region according to the compensation treatment profile to compensate for changes in temperature of the subcutaneous lipid-rich region associated with the identified interruption;

determining a third duration based on the total duration and the first duration; and

after compensating for the identified interruption, continuing the treatment process according to the profile based on the third duration.

11. The method of claim 10 , further comprising:

determine whether to resume the treatment process based on the interrupt duration and/or a number of interruption occurrences;

if the determination is to resume the treatment process, the treatment process is continued according to the profile for the third duration; and

if the determination is to not resume the treatment process, the treatment process is terminated.

12. The method of claim 10 , wherein the third duration is equal to a difference between the total duration and the first duration.

13. The method of claim 10 , further comprising:

determining a recovery cooling/heating rate based on the interrupt duration; and

cooling or heating the subcutaneous lipid-rich region based on the recovery cooling/heating rate to compensate for the temperature changes of the subcutaneous lipid-rich region associated with the identified interruption.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2013
From: ALLISON, JOHN W.
To: ZELTIQ AESTHETICS, INC.
Reel/Frame 030396/0977 →
Continuity (2)
Continuation 12337544 · Dec 17, 2008
Related Publication 20130245731A1 · Sep 19, 2013