Surgical devices and methods of use thereof

1. A method, comprising:

obtaining a first image from a first imaging modality;

identifying on the first image from the first imaging modality at least one element, wherein the at least one element comprises a landmark, an area of interest, an incision point, a bifurcation, an organ, or any combination thereof;

obtaining a second image from a second imaging modality;

generating an augmented bronchogram image from the second imaging modality, wherein the augmented bronchogram image is generated by:

placing a radiopaque instrument inside a body cavity at a first position, generating a first image of the radiopaque instrument inside the body cavity at the first position,

placing the radiopaque instrument inside the body cavity at a second position, generating a second image of the radiopaque instrument inside the body cavity at the second position,

superpositioning the first image of the radiopaque instrument inside the body cavity at the first position with the second image of the radiopaque instrument inside the body cavity at the second position to generate the augmented bronchogram;

wherein the first position and the second position are different;

wherein the augmented bronchogram is a map of a bronchial airway tree;

generating a compatible virtual image from the first image from the first imaging modality;

coarse registering of the augmented bronchogram from the second imaging modality to the compatible virtual image from the first imaging modality;

fine registering of the augmented bronchogram image from the second imaging modality to the compatible virtual image from the first imaging modality;

generating a third image; wherein the third image is an augmented image including a highlighted area of interest,

wherein the highlighted area of interest can be determined by a method selected from the group consisting of:

(i) bolding a portion of the augmented bronchogram image,

(ii) coloring the portion of the augmented bronchogram image,

(iii) enhancing the portion of the augmented bronchogram image,

(iv) super-positioning a graphic over the augmented bronchogram image,

(v) or any combination thereof.

2. The method of claim 1 , further comprising superimposing the first image, a portion of the first image, or a first planning data derived from the first imaging modality over the second image of the second imaging modality.

3. The method of claim 1 , further comprising using at least one instruction, wherein the at least one instruction can include information regarding navigation, guidance, or a combination thereof.

4. The method of claim 3 , wherein the guidance includes information regarding the first position of the radiopaque instrument shown by the second imaging modality, wherein the radiopaque instrument comprises a fluoroscopic C-Arm, to result in achieving visibility for the area of interest, incision points, anatomical structures, or tool access direction.

5. The method of claim 1 , further comprising tracking of at least one anatomical structure by use of at least one subsequent image derived from the second imaging modality,

wherein the second imaging modality comprises a fluoroscopic video configured to have substantially the same acquisition parameters, and

wherein the acquisition parameters comprise mode, position, field of view, or any combination thereof, to generate the augmented fluoroscopic image by suppressing static anatomic structures, improving signal to noise of underlying soft tissue, or any combination thereof.

6. The method of claim 1 , further comprising performing a multiphase registration,

wherein the at least one substantially static object is first registered; and

wherein at least one dynamic object is second registered,

wherein the at least one dynamic object comprises a diaphragm, a bronchus, a blood vessel, or any combination thereof.

7. The method of claim 1 , further comprising deemphasizing at least one interfering structure.

8. The method of claim 2 , wherein the compatible virtual image is not generated while the planning data from first imaging modality is transferred to second imaging modality by means of image registration.

9. The method of claim 1 , wherein the augmented bronchogram is a partial map of the bronchial airway tree.

10. The method of claim 1 , wherein the augmented bronchogram is a complete map of the bronchial airway tree.

11. The method of claim 1 , wherein the augmented bronchrogram image is further generated by a method selected from the group consisting of:

a) superpositioning the first position of the radiopaque instrument, the second position of the radiopaque instrument in the body cavity, and their correspondent angular measurement of a C-arm orientation relative to the patient, or any combination thereof;

b) using a radiopaque instrument configured to reconstruct a three-dimensional space from a single projection;

b) or any combination thereof.