IP Library Granted Patent US 9,752,174
Granted Patent B2
US 9,752,174 · App. 14/287,837 · Granted Sep 5, 2017

High-purity steviol glycosides

Inventors: Avetik Markosyan (Yerevan, AM); Indra Prakash (Alpharetta, GA); Cynthia Bunders (Atlanta, GA); Pankaj Soni (Kennesaw, GA); Jarrin Cyrille (Muret, FR); Aurélien Badie (Lebège, FR); Robert ter Halle (Baziege, FR)
Assignees: PureCircle Sdn Bhd; The Coca-Cola Company
C12P19/56A23L2/60A23L27/33A24B15/10A24B15/302C07H15/256A23V2002/00Y02P20/582
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Quick Facts
Patent No.
US 9,752,174
App. No.
14/287,837
Granted
Sep 5, 2017
Kind
B2
Abstract

Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

Claims (8)

1. A method for preparing reb D2 comprising:

a. contacting a starting composition comprising reb A with UDP-glucosyltransferase, to produce a composition comprising reb D2; and

b. isolating the composition comprising reb D2.

2. The method of claim 1 , further comprising purifying the composition comprising reb D2 to provide reb D2 having a purity greater than about 95% by weight on an anhydrous basis.

3. A method for preparing reb M2 comprising:

a. contacting a starting composition comprising reb D2 with UDP-glucosyltransferase to produce a composition comprising reb M2; and

b. isolating the composition comprising reb M2.

4. The method of claim 3 , further comprising purifying the composition comprising reb M2 to provide reb M2 having a purity greater than about 95% by weight on an anhydrous basis.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2018
From: THE COCA-COLA COMPANY
To: PURECIRCLE SDN BHD
Reel/Frame 046787/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 2017
From: MARKOSYAN, AVETIK; PRAKASH, INDRA; BUNDERS, CYNTHIA; SONI, PANKAJ; CYRILLE, JARRIN; BADIE, AURELIEN; TER HALLE, ROBERT
To: PURECIRCLE SDN BHD; THE COCA-COLA COMPANY
Reel/Frame 042448/0431 →
Continuity (11)
Provisional Application 61827922 · May 28, 2013
Provisional Application 61843544 · Jul 8, 2013
Provisional Application 61861528 · Aug 2, 2013
Provisional Application 61881166 · Sep 23, 2013
Provisional Application 61885084 · Oct 1, 2013
Provisional Application 61904751 · Nov 15, 2013
Provisional Application 61913482 · Dec 9, 2013
Provisional Application 61921635 · Dec 30, 2013
Provisional Application 61925329 · Jan 9, 2014
Provisional Application 61939855 · Feb 14, 2014
Related Publication 20140357588A1 · Dec 4, 2014