IP Library Granted Patent US 9,789,146
Granted Patent B1
US 9,789,146 · App. 15/452,688 · Granted Oct 17, 2017

Synthesis of adansonia digitata nanoparticles

Inventors: Manal Ahmed Gasmelseed Awad (Riyadh, SA); Awatif Ahmed Hendi (Riyadh, SA); Khalid Mustafa Osman Ortashi (Riyadh, SA)
Assignee: KING SAUD UNIVERSITY
A61K36/185A61K9/5138A61K9/5161A61K9/5192A61K2236/333A61K2236/39A61K2236/51
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Quick Facts
Patent No.
US 9,789,146
App. No.
15/452,688
Granted
Oct 17, 2017
Kind
B1
Abstract

A method of preparing Adansonia digitata nanoparticles includes dissolving Adansonia digitata plant powder in an organic solvent to form a solution; spraying the solution in boiling water while applying ultrasonic energy to form a mixture; and stirring the mixture for at least about 15 minutes at a speed of about 200-800 rpm to obtain the Adansonia digitata nanoparticles.

Claims (10)

1. A method of synthesizing Adansonia digitata nanoparticles, comprising:

dissolving Adansonia digitata plant powder in an organic solvent selected from the group consisting of at least one of methanol, ethanol, dichloromethane, and chloroform to form a solution;

adding about 1 ml to about 4 ml of the solution to about 50 ml to about 100 ml of boiling water under ultrasonic conditions to form a mixture; and;

stirring the mixture at a speed of about 200 rpm to about 800 rpm to obtain Adansonia digitata nanoparticles,

wherein the ultrasonic conditions include sonication for about 10 minutes to about 20 minutes with an ultrasonic power of 100 W and a frequency of 30 kHz prior to being stirred, and

wherein the Adansonia digitata nanoparticles have a mean diameter in the range of from about 50 nm to about 300 nm.

2. The method of synthesizing Adansonia digitata nanoparticles according to claim 1 , further comprising isolating and drying the Adansonia digitata nanoparticles to obtain dried Adansonia digitata nanoparticle powder.

3. The method of synthesizing Adansonia digitata nanoparticles according to claim 1 , wherein the Adansonia digitata plant powder is derived from the fruit pulp of Adansonia digitata.

4. The method of preparing Adansonia digitata nanoparticles according to claim 1 , wherein the solution is added to the boiling water by spraying the solution dropwise into the boiling water at a rate of about 0.2 ml/minute in about 5 minutes.

5. The method of synthesizing Adansonia digitata nanoparticles according to claim 1 , wherein the Adansonia digitata nanoparticles have spherical, spheroidal, elongated, spherical, rod-shaped, and/or faceted shapes.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 7, 2017
From: AWAD, MANAL AHMED GASMELSEED, MR.; HENDI, AWATIF AHMED, MR.; ORTASHI, KHALID MUSTAFA OSMAN, MR.
To: KING SAUD UNIVERSITY
Reel/Frame 041490/0023 →