Diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD)
The present invention refers to diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD).
1. A method of treating attention deficit hyperactivity disorder (ADHD) in a human, the method comprising:
testing diamine oxidase (DAO) activity level in plasma of the human;
responsive to results of the testing being less than or equal to a pre-defined threshold, orally administering a dosage of 0.1-50 mg of DAO to the human; and
wherein the pre-defined threshold is not greater than 80 HDU/ml.
2. The method according to claim 1 , wherein the DAO is administered in at least one of tablets, capsules, and sachets.
3. The method according to claim 1 , wherein the dosage is 2-20 mg.
4. The method according to claim 1 , further comprising administering caffeine to the human.
5. The method according to claim 4 , wherein a dosage of the administered caffeine is 1-100 mg.
6. The method according to claim 1 , wherein the administered DAO is provided with gastric protection.
7. The method according to claim 1 , wherein a form of the administered DAO is selected from the group consisting of free form, powder, lyophilised powder, microcapsules, nanocapsules, and liposomes.
8. The method according to claim 1 , wherein the DAO is included in a composition.
9. The method according to claim 5 , wherein the dosage of the administered caffeine is 5-50 mg.
10. The method according to claim 8 , wherein the composition has an enteric coating that protects the DAO from gastric acidity.