IP Library Granted Patent US 9,795,654
Granted Patent B2
US 9,795,654 · App. 14/394,589 · Granted Oct 24, 2017

Diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD)

Inventors: Carlos Duelo Riu (Barcelona, ES); Juan José Duelo Riu (Barcelona, ES)
Assignee: DR HEALTHCARE ESPAÑA, S.L.
A61K38/44A61K9/16A61K9/48A61K9/50A61K31/522C12N9/0022C12Y104/03006
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,795,654
App. No.
14/394,589
Granted
Oct 24, 2017
Kind
B2
Abstract

The present invention refers to diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD).

Claims (13)

1. A method of treating attention deficit hyperactivity disorder (ADHD) in a human, the method comprising:

testing diamine oxidase (DAO) activity level in plasma of the human;

responsive to results of the testing being less than or equal to a pre-defined threshold, orally administering a dosage of 0.1-50 mg of DAO to the human; and

wherein the pre-defined threshold is not greater than 80 HDU/ml.

2. The method according to claim 1 , wherein the DAO is administered in at least one of tablets, capsules, and sachets.

3. The method according to claim 1 , wherein the dosage is 2-20 mg.

4. The method according to claim 1 , further comprising administering caffeine to the human.

5. The method according to claim 4 , wherein a dosage of the administered caffeine is 1-100 mg.

6. The method according to claim 1 , wherein the administered DAO is provided with gastric protection.

7. The method according to claim 1 , wherein a form of the administered DAO is selected from the group consisting of free form, powder, lyophilised powder, microcapsules, nanocapsules, and liposomes.

8. The method according to claim 1 , wherein the DAO is included in a composition.

9. The method according to claim 5 , wherein the dosage of the administered caffeine is 5-50 mg.

10. The method according to claim 8 , wherein the composition has an enteric coating that protects the DAO from gastric acidity.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2014
From: DUELO RIU, CARLOS; DUELO RIU, JUAN JOSÉ
To: DR HEALTHCARE ESPAÑA, S.L.
Reel/Frame 034148/0674 →
Priority Claims (1)
ES 201230578 · Apr 18, 2012 · national
Continuity (1)
Related Publication 20150093430A1 · Apr 2, 2015