Synthetic structure for soft tissue repair

1. A synthetic structure for repair of a rotator cuff comprising a polymeric fibrillar structure having a length and a width and having uniform fibrillar distribution, a stiffness of about 10 to about 500 Newtons per millimeter (N/mm) along the length and along the width, and at least one fiber having a diameter ranging from about 10 microns to about 200 microns, wherein the fibrillar structure is a planar woven structure, the planar woven structure exhibiting mechanical properties of human rotator cuff tendon.

2. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure is bioabsorbable.

3. The synthetic structure of claim 2 , wherein the polymeric fibrillar structure is fabricated from at least a member selected from the group consisting of glycolide, lactide, trimethylene carbonate, dioxanone, caprolactone, alkylene oxides, ortho esters, polymers and copolymers thereof, collagen, hyaluronic acids, alginates, and combinations thereof.

4. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure is non-bioabsorbable.

5. The synthetic structure of claim 4 , wherein the polymeric fibrillar structure is fabricated from at least a member of the group consisting of polypropylene, polyethylene, polyamide, polyalkylene terephthalate, polyvinylidene fluoride, polytetrafluoroethylene and blends and copolymers thereof.

6. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure exhibits a tensile strength of about 20 to about 2000 Newtons.

7. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure exhibits a failure strain at 105% to about 150% of original length.

8. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure exhibits a tensile strength of at least about 220 Newtons.

9. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure has about 10 to about 150 warp fibers per inch.

10. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure has about 30 to about 100 warp fibers per inch.

11. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure has about 50 to about 75 warp fibers per inch.

12. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure is knitted.

13. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure is non-woven.

14. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure comprises at least one fiber having a diameter ranging from about 30 microns to about 100 microns.

15. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure comprises at least one fiber having a diameter ranging from about 50 microns to about 80 microns.

16. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure comprises at least two fibers of different diameters.

17. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure has at least two layers.

18. The synthetic structure of claim 1 , wherein the polymeric fibrillar structure includes a bioactive agent thereon.

19. The synthetic structure of claim 18 wherein the bioactive agent is selected from the group consisting of extracellular matrix molecules, growth factors and hyaluronic acid.

20. A synthetic structure for repair of a rotator cuff comprising a polymeric fibrillar structure, wherein the fibrillar structure comprises two planar woven layers having the same mechanical properties, the fibrillar structure exhibiting a stiffness of about 10 to about 500 Newtons per millimeter (N/mm), a tensile strength of about 20 to about 2000 Newtons and a failure strain at 105% to about 150% of original length.

21. A synthetic structure comprising:

a rectangular, bioabsorbable polymeric fibrillar structure configured for human rotator cuff tendon repair and having two planar woven layers, each of the two planar woven layers having the same mechanical properties and a uniform fibrillar distribution.