IP Library Granted Patent US 9,820,913
Granted Patent B2
US 9,820,913 · App. 13/992,191 · Granted Nov 21, 2017

Aseptic cartridge and dispenser arrangement

Inventor: Amir Genosar (Boulder, CO)
Assignee: AKTIVAX, INC.
A61J1/2093A61J1/2096A61M5/2448A61M5/2455A61M5/28A61M5/284A61M5/285B65D75/367B65D75/368A61J1/067A61J1/201A61J1/2024B65D2221/00
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Quick Facts
Patent No.
US 9,820,913
App. No.
13/992,191
Granted
Nov 21, 2017
Kind
B2
Abstract

A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments, and a fitment. The first compartment contains at least a first constintuent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.

Claims (31)

1. A cartridge for use with a beneficial agent delivery device having a fillable reservoir, said cartridge comprising:

a package, comprising:

a first compartment containing at least a first constintuent of the beneficial agent;

wherein at least a portion of the first compartment is formed by a flexible wall preformed in the shape of a tube; and

a fitment disposed on said package configured to interface said package to the fillable reservoir of the delivery device;

a fluid passageway between said package and the delivery device; and

a static mixer disposed in the fluid passageway.

2. The cartridge of claim 1 wherein the cartridge is adapted to communicate with a delivery portion of the delivery device that comprises one of a needle, a connector and a nozzle.

3. The cartridge of claim 1 further comprising a second compartment and wherein said first compartment is segregated from said second compartment by a rupturable barrier.

4. The cartridge of claim 1 wherein at least a portion of said flexible wall comprises a peelable foil layer.

5. The cartridge of claim 3 further comprising a fluid passageway between said first compartment and said second compartment.

6. The cartridge of claim 5 further comprising a static mixer disposed in said fluid passageway.

7. The cartridge of claim 1 further comprising a filling compartment, a fluid passageway, and first and second package walls, the filling compartment being in fluid communication with said first compartment via said fluid filling passageway.

8. The cartridge of claim 7 wherein said filling compartment is located between the first and second walls of said package.

9. The cartridge of claim 7 wherein said fluid passageway is sealable to prevent backflow to the filling compartment during or after filling.

10. The cartridge of claim 7 further comprising a thermal seal between the first and second walls of said package to seal said fluid passageway.

11. The cartridge of claim 7 further comprising an isolation valve disposed in at least one of said filling compartment and said filling passageway.

12. The cartridge of claim 7 wherein said filling compartment is at least partially defined by a well formed in at least one of said first and second walls of said package.

13. The cartridge of claim 7 further comprising a filling system configured to communicate with said filling compartment through a fluid tight seal.

14. The cartridge of claim 7 wherein said filling passageway is formed to direct fluid of the fluid dose package along the first wall of said first compartment to prevent jetting.

15. The cartridge of claim 7 further comprising a gas evacuation chamber in communication with said first compartment via a fluid evacuation passageway, said fluid evacuation passageway being sealable to prevent flow from said first compartment after filling.

16. The cartridge of claim 1 further comprising a closure segregating said first compartment from said fitment until opened.

17. A cartridge for use with a beneficial agent delivery device having a fillable reservoir, said cartridge comprising:

a package, comprising:

a first compartment containing at least a first constintuent of the beneficial agent;

wherein at least a portion of the first compartment is formed by a flexible wall preformed in the shape of a tube;

a fitment disposed on said package configured to interface said package to the fillable reservoir of the delivery device;

a second compartment;

a fluid passageway between said first compartment and said second compartment; and

a static mixer disposed in said fluid passageway;

wherein said first compartment is segregated from said second compartment by a rupturable barrier.

Assignments (3)
SECURITY INTEREST Recorded Aug 17, 2020
From: AKTIVAX, INC.
To: LIVE OAK BANKING COMPANY
Reel/Frame 053509/0524 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2020
From: GENOSAR, AMIR
To: AKTIVAX, INC.
Reel/Frame 051590/0657 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2013
From: GENOSAR, AMIR
To: AKTIVAX, INC.
Reel/Frame 031186/0655 →
Continuity (7)
Provisional Application 61419892 · Dec 6, 2010
Provisional Application 61433493 · Jan 17, 2011
Provisional Application 61467359 · Mar 24, 2011
Provisional Application 61487121 · May 17, 2011
Provisional Application 61523422 · Aug 15, 2011
Provisional Application 61533194 · Sep 10, 2011
Related Publication 20140053952A1 · Feb 27, 2014