Dialysis systems and related methods
A dialysis machine that includes a valve member having a deformable area configured to deform outwardly away when pressurized fluid is introduced into the valve member. The valve member is configured so that, when a dialysis fluid cassette is disposed in a cassette compartment of the dialysis machine and pressurized fluid is introduced into the valve member, the deformable area obstructs a fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough.
1. A dialysis machine, comprising:
a machine block;
a door that, when closed, cooperates with the machine block to define a cassette compartment configured to receive a dialysis fluid cassette that comprises a fluid channel formed between a base and a flexible membrane that is attached to the base, the cassette compartment being configured such that the membrane of the dialysis fluid cassette is positioned adjacent the machine block when the dialysis fluid cassette is disposed in the cassette compartment of the dialysis machine; and
a valve member secured to the machine block in a manner such that the valve member is substantially aligned with a portion of the fluid channel of the dialysis fluid cassette when the dialysis fluid cassette is disposed in the cassette compartment, the valve member comprising a deformable area configured to deform outwardly, upon being pressurized by fluid introduced into the valve member, a sufficient extent to obstruct the fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough when the dialysis fluid cassette is disposed in the cassette compartment.
2. The dialysis machine of claim 1 , further comprising a pressurized air source fluidly connected to the valve member such that pressurized air can be delivered from the pressurized air source to the valve member.
3. The dialysis machine of claim 1 , further comprising a vacuum source fluidly connected to the valve member such that vacuum pressure can be applied to the valve member by the vacuum source to move the deformable area of the valve member from an outwardly deformed position to an undeformed or an inwardly deformed position.
4. The dialysis machine of claim 1 , further comprising an inflatable pad configured to press the dialysis fluid cassette against the machine block when the dialysis fluid cassette is disposed in the cassette compartment.
5. The dialysis machine of claim 1 , wherein the door is connected to the machine block via a hinge.
6. The dialysis machine of claim 1 , wherein the machine block and the door are configured so that, when the dialysis fluid cassette is disposed in the cassette compartment, the flexible membrane of the dialysis fluid cassette is substantially parallel to an adjacent face of the machine block.
7. The dialysis machine of claim 1 , wherein the valve member comprises a valve body defining a pressure passage and a sealing cap disposed at a first end of the valve body such that the sealing cap closes off the pressure passage at the first end of the valve body, the sealing cap forming the deformable area, which is configured to deform outwardly away from the valve body when pressurized fluid is introduced into the pressure passage of the valve body.
8. The dialysis machine of claim 7 , wherein the sealing cap has a radially inwardly directed projection configured to prevent direct contact of the valve body with the deformable area of the sealing cap.
9. The dialysis machine of claim 7 , further comprising a fastening component coupled to a second end of the valve body opposite the first end, the fastening component configured to abut the machine block to secure the valve member to the machine block.
10. The dialysis machine of claim 7 , wherein the sealing cap is detachable from the valve body.
11. The dialysis machine of claim 1 , wherein the dialysis machine is a hemodialysis machine.
12. A dialysis system comprising:
a dialysis fluid cassette that comprises a fluid channel formed between a base and a flexible membrane that is attached to the base; and
a dialysis machine comprising
a machine block;
a door that, when closed, cooperates with the machine block to define a cassette compartment configured to receive the dialysis fluid cassette in a manner such that the membrane of the dialysis fluid cassette is positioned adjacent the machine block when the dialysis fluid cassette is disposed in the cassette compartment of the dialysis machine; and
a valve member secured to the machine block in a manner such that the valve member is substantially aligned with a portion of the fluid channel of the dialysis fluid cassette when the dialysis fluid cassette is disposed in the cassette compartment, the valve member comprising a deformable area configured to deform outwardly, upon being pressurized by fluid introduced into the valve member, a sufficient extent to obstruct the fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough when the dialysis fluid cassette is disposed in the cassette compartment.
13. The dialysis system of claim 12 , wherein the dialysis system is configured to cause dialysate to flow through the fluid channel of the dialysis fluid cassette.
14. The dialysis system of claim 13 , wherein the dialysis system is configured to cause blood to flow through the fluid channel of the dialysis fluid cassette.
15. The dialysis system of claim 12 , wherein the base of the dialysis fluid cassette is rigid.
16. The dialysis system of claim 12 , wherein the base of the dialysis fluid cassette defines a recessed region and comprises raised rims extending outward from a planar surface of the base along edges of the recessed region, the raised rims configured to contact the flexible membrane when the flexible membrane is pressed against the base to form the fluid channel between the flexible membrane and the recessed region of the base.
17. The dialysis system of claim 12 , wherein the base and the flexible membrane of the dialysis fluid cassette form a pump chamber therebetween, and the pump chamber is connected to the fluid channel such that operation of the valve member can control fluid flow to or from the pump chamber.
18. The dialysis system of claim 12 , wherein the dialysis system further comprises a pressurized air source fluidly connected to the valve member such that pressurized air can be delivered from the pressurized air source to the valve member.
19. The dialysis system of claim 12 , wherein the dialysis system further comprises a vacuum source fluidly connected to the valve member such that vacuum pressure can be applied to the valve member by the vacuum source to move the deformable area of the valve member from an outwardly deformed position to an undeformed or an inwardly deformed position.
20. The dialysis system of claim 12 , wherein the dialysis machine comprises an inflatable pad configured to press the dialysis fluid cassette against the machine block when the dialysis fluid cassette is disposed in the cassette compartment.
21. The dialysis system of claim 12 , wherein the door is connected to the machine block via a hinge.
22. The dialysis system of claim 12 , wherein the machine block, the door, and the dialysis fluid cassette are configured so that, when the dialysis fluid cassette is disposed in the cassette compartment, the flexible membrane of the dialysis fluid cassette is substantially parallel to an adjacent face of the machine block.
23. The dialysis system of claim 12 , wherein the valve member comprises a valve body defining a pressure passage and a sealing cap disposed at a first end of the valve body such that the sealing cap closes off the pressure passage at the first end of the valve body, the sealing cap forming the deformable area, which is configured to deform outwardly away from the valve body when pressurized fluid is introduced into the pressure passage of the valve body.
24. The dialysis system of claim 23 , wherein the sealing cap has a radially inwardly directed projection configured to prevent direct contact of the valve body with the deformable area of the sealing cap.
25. The dialysis system of claim 23 , further comprising a fastening component coupled to a second end of the valve body opposite the first end, the fastening component configured to abut the machine block to secure the valve member to the machine block.
26. The dialysis system of claim 23 , wherein the sealing cap is detachable from the valve body.
27. The dialysis system of claim 12 , wherein the dialysis machine is a hemodialysis machine.
28. The dialysis system of claim 12 , wherein the dialysis fluid cassette comprises a plurality of fluid channels formed between the base and the flexible membrane that is attached to the base, and the dialysis machine comprises a plurality of valve members secured to the machine block, each of the valve members being substantially aligned with a portion of one of the fluid channels of the dialysis fluid cassette when the dialysis fluid cassette is disposed in the cassette compartment of the dialysis machine, and each of the valve members comprising a deformable area configured to deform outwardly, upon being pressurized by fluid introduced into the valve member, a sufficient extent to obstruct the aligned portion of the fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough when the dialysis fluid cassette is disposed in the cassette compartment of the dialysis machine.
29. The dialysis system of claim 28 , wherein a plurality of pump chambers are formed between the base and the flexible membrane of the dialysis fluid cassette, and the dialysis machine comprises a plurality of pumps, each of the pumps being aligned with one of the pump chambers, and each of the fluid channels being connected to one or more of the pump chambers such that the pumps can be operated to force dialysis fluid through the fluid channels of the dialysis fluid cassette.