Wound dressing materials incorporating anthocyanins derived from fruit or vegetable sources
View Patent ↗A wound dressing composition, such as gauze, bandages, and surgical tapes comprising a substrate material impregnated with a pH sensitive dye composition comprising at least one anthocyanin derived from fruit or vegetable sources, and methods of use thereof.
1. A wound dressing, comprising
a substrate material; and
a pH sensitive dye composition fixed to the substrate material by a mordant comprising aluminum potassium sulfate, wherein the pH sensitive dye composition comprises at least one fruit or vegetable derived anthocyanin, and the substrate material comprises a fabric, cloth or sponge material, and wherein color of the pH sensitive dye composition indicates pH of a wound.
2. The dressing of claim 1 , wherein the at least one anthocyanin is derived from a raspberry ( Rubus sp.).
3. The dressing of claim 1 , wherein the at least one anthocyanin is derived from a fruit or vegetable selected from the group consisting of a red cabbage, purple cabbage, purple carrots, elderberry, hibiscus, purple potato, red currant, black currants, blueberries, cherries, purple grapes, red raspberries and black raspberries.
4. The dressing of claim 1 , wherein the substrate material is a woven or non-woven material.
5. The dressing of claim 1 , where the substrate material comprises natural or synthetic fibers.
6. The dressing of claim 1 , where the substrate material is an absorbent or water-permeable material.
7. The dressing of claim 1 , where the substrate material comprises cotton.
8. The dressing of claim 1 , wherein the substrate material comprises cotton gauze.
9. The dressing of claim 1 , wherein the dressing is selected from the group consisting of a pad, wrap, bandage, tape, cotton-tipped stick and adhesive strip bandage.
10. The dressing of claim 1 , wherein the at least one anthocyanin is selected from the group consisting of cyaniding-3-sophoraside, cyanide-3-glucoside and pelargonidin-3-sophoroside.
11. The dressing of claim 1 , wherein the at least one anthocyanin is an anthocyanadin derivative selected from the group consisting of cyandin, delphinidin, peonidin, petunidin, pelargonidin and malvidin anthocyanadin derivatives.
12. The dressing of claim 1 , wherein the pH sensitive dye composition is sensitive at least within a pH range of pH 4.0 to pH 12.0, inclusive.
13. The dressing of claim 1 , wherein the dressing further comprises at least one therapeutic agent selected from the group consisting of antimicrobial agents, antiseptic agents, anti-inflammatory agents, pain relieving agents, wound closing adhesive agents, and antihistamine agents.
14. The dressing of claim 1 , wherein color of the fruit or vegetable derived anthocyanin pH sensitive dye fixed to the substrate material is an indicator of the status of a wound.
15. The dressing of claim 1 , wherein the mordant does not comprise magnesia.