Applicators for storing, sterilizing, and dispensing an adhesive

1. An applicator for storing and dispensing an adhesive comprising:

a) a container comprising walls defining a chamber, the walls comprising a copolymer of acrylonitrile and methyl acrylate or comprising multiple layers with the inner-most layer comprising a copolymer of acrylonitrile and methyl acrylate, and a frangible seal covering a proximal end of the chamber, the frangible seal having a side in communication with a stabilized cyanoacrylate monomer adhesive stored in the chamber;

b) a body comprising a proximal end and a distal end, a flange extending from the proximal end of the body comprising at least one hole, a reservoir in communication with the hole, the reservoir extending through the body, and having an opening at the distal end of the body and a grip capable of constricting the reservoir when inward pressure is applied to the grip,

wherein the flange is capable of penetrating the frangible seal when the body and the container are compressed together; and

c) a porous tip in communication with the opening of the reservoir;

wherein the applicator is activated by compressing the body and the container together whereupon the flange penetrates the frangible seal and allows the adhesive to flow into the hole, through the reservoir, and out of the porous tip, and wherein at least the container is sterilized by radiation, and the adhesive stored in the container does not cure upon radiation exposure and for at least about twelve months of shelf storage thereafter.

2. The applicator of claim 1 , wherein the cyanoacrylate monomer adhesive comprises a monomer of 2-octyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, methyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, or 1-methoxy-2-propyl cyanoacrylate.

3. The applicator of claim 1 , wherein the adhesive stored in the chamber of the container does not cure upon radiation exposure for at least about twenty four months of shelf storage thereafter.

4. The applicator of claim 1 , wherein the porous tip comprises a swab, sponge, foam, or a brush.

5. The applicator of claim 1 , further comprising a tip overlay removably placed over the top of the porous tip.

6. The applicator of claim 1 , further comprising a removable lock between the container and the body that prevents the body and the container from being compressed together and that, when removed, allows the body and the container to be compressed together.

7. An applicator for storing and dispensing an adhesive comprising:

a) a handle with a first proximal end and a first distal end, and defining a housing for a removable adhesive container comprising a copolymer of acrylonitrile and methyl acrylate or multiple layers with the inner-most layer comprising a copolymer of acrylonitrile and methyl acrylate, the container being capable of fitting within the housing, and further comprising a frangible seal covering an end of the container and having a side in communication with a stabilized cyanoacrylate monomer adhesive stored in the container;

b) a female end of a luer lock at the first distal end;

c) a body including a second proximal end and a second distal end and containing a reservoir extending through the body having an opening at the second distal end;

d) a male end of a luer lock at the second proximal end and capable of connecting to the female end of the luer lock; and

e) a porous tip in communication with the reservoir opening,

wherein the applicator is activated by compromising the frangible seal whereupon the adhesive may flow into and through the reservoir and out of the porous tip, and wherein at least the container is sterilized by radiation, and the adhesive stored in the container does not cure upon radiation exposure and for at least about twelve months of shelf storage thereafter.

8. The applicator of claim 7 , wherein the cyanoacrylate monomer adhesive comprises a monomer of 2-octyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, methyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, or 1-methoxy-2-propyl cyanoacrylate.

9. The applicator of claim 7 , wherein the container is a stick pack container.

10. The applicator of claim 7 , wherein the frangible seal comprises aluminum foil laminated with a copolymer of acrylonitrile and methyl acrylate on the side in communication with the adhesive stored in the container.

11. The applicator of claim 7 , wherein the adhesive stored in the chamber of the container does not cure upon radiation exposure and for at least about twenty four months of shelf storage thereafter.

12. The applicator of claim 7 , wherein the porous tip comprises a swab, sponge, foam, or a brush.

13. The applicator of claim 7 , further comprising a tip overlay removably placed over the top of the porous tip.

14. An applicator for storing and dispensing an adhesive comprising:

a) a container including a wall, an opening, and a chamber containing a stabilized cyanoacrylate monomer adhesive;

b) the wall further comprising a copolymer of acrylonitrile and methyl acrylate or multiple layers with the inner-most layer comprising a copolymer of acrylonitrile and methyl acrylate;

c) a first screw thread on the exterior of the wall;

d) a frangible seal covering the opening;

e) a body having a proximal end, a distal end, and a reservoir extending through the body with a reservoir opening at the distal end;

f) a second screw thread on the interior of the body for engaging the first screw thread;

g) the exterior of the body defining a flexible grip capable of constricting the reservoir when inward pressure is applied to the grip;

h) at least one projection attached to the interior of the body, wherein the projection is capable of penetrating the frangible seal when the body and the container are compressed together, and

i) a porous tip in communication with the reservoir opening wherein the applicator is activated by screwing the body and the container together whereupon the projection penetrates the frangible seal and allows the adhesive to flow into and through the reservoir and out of the porous tip, and wherein at least the container is sterilized by radiation, and the adhesive stored in the chamber of the container does not cure upon radiation exposure and for at least about twelve months of shelf storage thereafter.

15. The applicator of claim 14 , wherein the cyanoacrylate monomer adhesive comprises a monomer of 2-octyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, methyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, or 1-methoxy-2-propyl cyanoacrylate.

16. The applicator of claim 14 , wherein the frangible seal comprises aluminum foil laminated with a copolymer of acrylonitrile and methyl acrylate on the side in communication with the chamber.

17. The applicator of claim 14 , wherein the adhesive stored in the chamber of the container does not cure upon radiation exposure and for at least about twenty four months of shelf storage thereafter.

18. The applicator of claim 14 , wherein the porous tip comprises a swab, sponge, foam, or a brush.

19. The applicator of claim 14 , further comprising a tip overlay removably placed over the top of the porous tip.

20. The applicator of claim 14 , further comprising a removable lock between the container and the body that prevents the body and the container from being connected together and that, when removed, allows the body and the container to be connected together.