IP Library Granted Patent US 9,987,162
Granted Patent B2
US 9,987,162 · App. 15/127,737 · Granted Jun 5, 2018

Mammalian head cooling system and method

Inventors: Ting-Yim Lee (London, CA); Mohammad Fazel Bakhsheshi (London, CA); Lynn Keenliside (Lucan, CA)
Assignee: THE UNIVERSITY OF WESTERN ONTARIO
A61F7/12A61M16/0666A61M16/0875A61M16/202A61F2007/0006A61F2007/0064A61F2007/0096A61M2205/3331A61M2205/3368A61M2205/3606A61M2206/16
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Quick Facts
Patent No.
US 9,987,162
App. No.
15/127,737
Granted
Jun 5, 2018
Kind
B2
Abstract

Described herein is a head cooling system comprising: a source of compressed breathable gas; a vortex tube comprising an inlet, a hot gas outlet and a cold gas outlet, the inlet operably connected to the source of compressed breathable gas; and an interface for delivering cooled gas to a nasopharyngeal cavity in fluid communication with the cold gas outlet. The head cooling system may be used in a method to reduce neurodegeneration in a subject, for example neurodegeneration from ischemia, anoxia, cardiac arrest, trauma or neurodegenerative disease. The head cooling system may also be used in a method to prophylactically protect a subject at risk of neurodegeneration, for example neurodegeneration from ischemia, anoxia, cardiac arrest, trauma or neurodegenerative disease.

Claims (30)

1. A head cooling system comprising:

a source of compressed breathable gas;

a vortex tube comprising an inlet, a hot gas outlet and a cold gas outlet, the inlet operably connected to the source of compressed breathable gas;

a nasal cannula configured to deliver cooled gas to the nasopharyngeal cavity of a subject, in fluid communication with the cold gas outlet; and

a bladder in fluid communication with the hot gas outlet, the bladder capturing at least a portion of gas flowing from the hot gas outlet, and the bladder sized and shaped to provide an exterior surface to contact a body region located between a neck and a pelvis of the subject.

2. The system of claim 1 , further comprising a temperature sensor coupled at or proximal to the nasal cannula, the temperature sensor generating a temperature signal indicative of a temperature level of the breathable gas flowing through the nasal cannula.

3. The system of claim 2 , further comprising a computer operably connected to the temperature sensor, the computer configured to receive the temperature signal and to determine the temperature level of the breathable gas and regulate a pressure of the breathable gas if the temperature level is outside of a predetermined temperature range.

4. The system of claim 3 , further comprising a pressure regulator fluidly coupled between the source of compressed breathable gas and the inlet of the vortex tube, the computer configured to generate a control signal to induce the pressure regulator to change from a first pressure setting to a second pressure setting if the temperature level is outside of the predetermined temperature range.

5. The system of claim 1 , wherein the vortex tube comprises an adjustable fraction control valve for adjusting the flow of hot gas at the hot gas outlet.

6. The system of claim 5 , further comprising a computer operably connected to the fraction control valve, the computer configured to generate a control signal to induce the fraction control valve to change from a first setting to a second setting when the computer determines that a temperature level of breathable gas flowing through the nasal cannula is outside of a predetermined temperature range.

7. The system of claim 1 , wherein the vortex tube comprises a muffler in fluid communication with the hot air outlet, a muffler in fluid communication with the cold air outlet, or a muffler in fluid communication with each of the hot air outlet and the cold air outlet respectively.

8. The system of claim 1 , wherein the nasal cannula is a Continuous Positive Air Pressure (CPAP) nasal cannula for treatment of sleep apnea.

9. The system of claim 1 , wherein the nasal cannula comprises two substantially parallel nasal prongs for insertion into nostrils, and each nasal prong is at least 2 centimeters in length and comprises at least one aperture for outlet of cooled gas.

10. The system of claim 1 , wherein the bladder has an annular shape.

11. The system of claim 1 , further comprising an oral cannula in fluid communication with the cold gas outlet.

12. A head cooling kit comprising:

a vortex tube comprising an inlet, a hot gas outlet and a cold gas outlet;

a nasal cannula configured to deliver cooled gas to the nasopharyngeal cavity, in fluid communication with the cold gas outlet;

instructions for operably connecting the inlet to a source of compressed breathable gas and securing the nasal cannula to a mammal; and

a bladder in fluid communication with the hot gas outlet, the bladder capturing at least a portion of gas flowing from the hot gas outlet, and the bladder sized and shaped to provide an exterior surface to contact a body region located between a neck and a pelvis.

13. The kit of claim 12 , further comprising a temperature sensor coupled at or proximal to the nasal cannula, the temperature sensor generating a temperature signal indicative of a temperature level of the breathable gas flowing through the nasal cannula.

14. The kit of claim 13 , further comprising a computer operably connected to the temperature sensor, the computer configured to receive the temperature signal and to determine the temperature level of the breathable gas and regulate a pressure of the breathable gas if the temperature level is outside of a predetermined temperature range.

15. The kit of claim 14 , further comprising a pressure regulator fluidly coupled between the source of compressed breathable gas and the inlet of the vortex tube, the computer configured to generate a control signal to induce the pressure regulator to change from a first pressure setting to a second pressure setting if the temperature level is outside of the predetermined temperature range.

16. The kit of claim 12 , wherein the vortex tube comprises an adjustable fraction control valve for adjusting the flow of hot gas at the hot gas outlet.

17. The kit of claim 16 , further comprising a computer operably connected to the fraction control valve, the computer configured to generate a control signal to induce the fraction control valve to change from a first setting to a second setting when the computer determines that a temperature level of breathable gas flowing through the nasal cannula is outside of a predetermined temperature range.

18. The kit of claim 12 , wherein the vortex tube comprises a muffler in fluid communication with the hot air outlet, a muffler in fluid communication with the cold air outlet, or a muffler in fluid communication with each of the hot air outlet and the cold air outlet respectively.

19. The kit of claim 12 , wherein the nasal cannula is a Continuous Positive Air Pressure (CPAP) nasal cannula for treatment of sleep apnea.

20. The kit of claim 12 , wherein the nasal cannula comprises two substantially parallel nasal prongs for insertion into nostrils, and each nasal prong is at least 2 centimeters in length and comprises at least one aperture for outlet of cooled gas.

21. The kit of claim 12 , wherein the bladder has an annular shape.

22. The kit of claim 12 , further comprising an oral cannula in fluid communication with the cold gas outlet.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 28, 2016
From: LEE, TING-YIM; FAZEL BAKHSHESHI, MOHAMMAD; KEENLISIDE, LYNN
To: THE UNIVERSITY OF WESTERN ONTARIO
Reel/Frame 039880/0363 →
Continuity (2)
Provisional Application 61968844 · Mar 21, 2014
Related Publication 20170143538A1 · May 25, 2017