IP Library › Granted Patent US 10,072,046
Granted Patent B2
US 10,072,046 · App. 15/127,931 · Granted Sep 11, 2018

Non-naturally occurring porcine reproductive and respiratory syndrome virus (PRRSV) and methods of using

Inventors: Hiep Lai Xuan Vu (Lincoln, NE); Fernando Osorio (Lincoln, NE); William W. Laegreid (Laramie, WY); Asit K. Pattnaik (Lincoln, NE); Fangrui Ma (Lincoln, NE)
Assignees: NUtech Ventures; The Board of Trustees of the University of Illinois
C07K14/005A61K39/12C12N7/00A61K2039/552C12N2770/10021C12N2770/10022C12N2770/10034
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Quick Facts
Patent No.
US 10,072,046
App. No.
15/127,931
Granted
Sep 11, 2018
Kind
B2
Abstract

A non-naturally occurring porcine reproductive and respiratory syndrome virus (PRRSV) is provided herein, and methods of making and using the non-naturally occurring PRRSV also are provided.

Claims (7)

1. A porcine reproductive and respiratory syndrome virus (PRRSV)-CON nucleic acid having the sequence shown in SEQ ID NO: 1.

2. A composition comprising the nucleic acid of claim 1 and a pharmaceutically acceptable carrier.

3. The composition of claim 2 , further comprising an adjuvant.

4. A virus particle comprising the PPRSV-CON nucleic acid of claim 1 .

5. A composition comprising the virus particle of claim 4 and a pharmaceutically acceptable carrier.

6. A method for imparting heterologous cross-protection against porcine reproductive and respiratory syndrome (PPRS) Type 2 strains in a porcine, comprising administering, to a porcine, an effective amount of the virus particle of claim 4 .

7. The method of claim 6 , wherein the administration is selected from the group consisting of intramuscularly, intraperitoneally, and orally.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 30, 2018
From: VU, HIEP LAI; OSORIO, FERNANDO; PATTNAIK, ASIT K.; MA, FANGRUI
To: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
Reel/Frame 045666/0542 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
To: NUTECH VENTURES
Reel/Frame 043906/0010 →
Continuity (2)
Provisional Application 61968465 · Mar 21, 2014
Related Publication 20170198016A1 · Jul 13, 2017