IP Library Granted Patent US 10,072,052
Granted Patent B2
US 10,072,052 · App. 15/112,646 · Granted Sep 11, 2018

Method for the synthesis of phycocyanin

Inventors: Chelsea Marie Brain (Newcastle upon Tyne, GB); Gary Stephen Caldwell (Ashington, GB)
Assignee: UNIVERSITY OF NEWCASTLE UPON TYNE
C07K14/415A23L29/269A61K8/30A61K8/492A61Q19/00C09B61/00C09D11/037C09D11/32C12M21/02C12M31/02A61K2800/10A61K2800/43
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Quick Facts
Patent No.
US 10,072,052
App. No.
15/112,646
Granted
Sep 11, 2018
Kind
B2
Abstract

The invention discloses microorganism cell culture conditions that result in increased cellular and media concentrations of a biological pigment. The invention has applications in use as a natural food colouring, as antioxidants in the food supplement industries, in the nutraceutical, pharmaceutical, and cosmeceutical industries, and a non-toxic ink. The method results in pigment that is relatively easy to separate from the microorganism culture.

Claims (6)

1. A method for the synthesis of a phycocyanin, the method comprising the steps of (i) culturing a cyanobacteria in a growth medium and (ii) providing a source of light, wherein the light consists of electromagnetic radiation consisting of a wavelength of between 670 and 690 nm; and wherein the cyanobacteria in culture synthesizes increased levels of a phycocyanin.

2. The method of claim 1 , wherein the cyanobacteria is Arthrospira or Spirulina.

3. The method of claim 1 , wherein the electromagnetic radiation comprises an optimum emission wavelength of 680 nm.

4. The method of claim 1 , wherein the increased levels of the synthesized phycocyanin are at least 4.5-fold greater than levels of synthesized phycocyanin in the same cyanobacteria separately cultured in the presence of white light.

5. The method of claim 4 , wherein the synthesized phycocyanin leaches from the cyanobateria.

6. The method of claim 1 , wherein the phycocyanin is selected from the group consisting of a Spirulina phycocyanin and an Arthrospira phycocyanin.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 30, 2021
From: THE UNIVERSITY OF NEWCASTLE UPON TYNE
To: TANTILLUS SYNERGY LIMITED
Reel/Frame 055088/0472 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2018
From: BRAIN, CHELSEA; CALDWELL, GARY
To: UNIVERSITY OF NEWCASTLE UPON TYNE
Reel/Frame 045376/0175 →
Continuity (3)
Provisional Application 61931723 · Jan 27, 2014
Provisional Application 62013479 · Jun 17, 2014
Related Publication 20160333059A1 · Nov 17, 2016