Devices for cooling the nasal cavity
A method for cerebral cooling is described using a cooling assembly, which includes first and second elongate tubular members adapted for insertion into a nasal cavity of a patient through the patient's nostrils. The elongate tubular members each have a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen. The cooling assembly also includes a manifold and a reservoir, which contains a pressurized fluid that includes a propellant having a boiling point less than 22° C. The elongate tubular members are inserted into the nasal cavity through the patient's nostrils and pressurized fluid is delivered onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and second elongate tubular members.
1. A method for cerebral cooling, the method comprising:
providing a cooling assembly including
a first elongate tubular member having a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen,
a second elongate tubular member having a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen,
a manifold in fluid communication with the lumens of the first and the second elongate tubular members, the manifold further communicating with a third elongate tubular member, and
a reservoir containing a pressurized fluid in communication with the third elongate tubular member, wherein the pressurized fluid includes a propellant having a boiling point less than 22° C.;
inserting the first elongate tubular member into a nasal cavity of a patient through a first nostril of the patient such that the plurality of ports are positioned in the nasal cavity;
inserting the second elongate tubular member into the nasal cavity through a second nostril of the patient such that the plurality of ports are positioned in the nasal cavity; and
delivering the pressurized fluid onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and the second elongate tubular members;
wherein a check valve is situated between the manifold and the first and the second elongate tubular members, the check valve preventing the delivery of pressurized fluid onto the surface of the nasal cavity until a minimum inlet pressure of the pressurized fluid is obtained.
2. The method of claim 1 , wherein the pressurized fluid further comprises a cooling fluid having a boiling point less than 37° C.
3. The method of claim 2 , wherein the cooling fluid having a boiling point less than 37° C. is selected from the group consisting of a perfluorocarbon, a hydrofluorocarbon, and a fluorocarbon.
4. A method for cerebral cooling, the method comprising:
providing a cooling assembly including
a first elongate tubular member having a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen,
a second elongate tubular member having a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen,
a manifold in fluid communication with the lumens of the first and the second elongate tubular members, the manifold further communicating with a third elongate tubular member, and
a reservoir containing a pressurized fluid in communication with the third elongate tubular member, wherein the pressurized fluid includes a propellant having a boiling point less than 22° C. and a cooling fluid having a boiling point less than 37° C.;
inserting the first elongate tubular member into a nasal cavity of a patient through a first nostril of the patient such that the plurality of ports are positioned in the nasal cavity;
inserting the second elongate tubular member into the nasal cavity through a second nostril of the patient such that the plurality of ports are positioned in the nasal cavity; and
delivering the pressurized fluid onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and the second elongate tubular members;
wherein a check valve is situated between the manifold and the first and the second elongate tubular members, the check valve preventing the delivery of pressurized fluid onto the surface of the nasal cavity until a minimum inlet pressure of the pressurized fluid is obtained.