IP Library Granted Patent US 10,143,391
Granted Patent B2
US 10,143,391 · App. 13/889,852 · Granted Dec 4, 2018

Implantable pressure sensor

Inventors: Margot S. Damaser (Cleveland Heights, OH); Steven Majerus (Cleveland, OH); Paul C. Fletter (Mt. Prospect, IL); Steven L. Garverick (Cleveland Hts., OH); Wen H. Ko (Cleveland Hts., OH); Paul Zaszczurynski (Sycamore, IL)
Assignees: CASE WESTERN RESERVE UNIVERSITY; THE CLEVELAND CLINIC FOUNDATION; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERNS AFFAIRS
A61B5/03A61B5/205A61B5/6874A61B5/6882A61B5/726A61B2560/0219
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Quick Facts
Patent No.
US 10,143,391
App. No.
13/889,852
Granted
Dec 4, 2018
Kind
B2
Abstract

Systems and methods are provided for in vivo measurement of pressure. An implantable sensor assembly includes a pressure sensor configured to provide an analog signal representing pressure and a signal conditioning component configured to convert the pressure sensor output into a digital signal. A transmitter is configured to transmit the digital signal to an external base unit. A power control unit is configured to dynamically allocate power throughout the implantable sensor assembly, such that during an active measurement interval of the implantable sensor assembly, each of the pressure sensor, the signal conditioning component, and the transmitter are powered only for a portion of the active measurement interval necessary to perform a related function.

Claims (17)

1. An in vivo sensor assembly comprising:

a pressure sensor configured to provide an analog signal representing pressure;

a signal conditioning component configured to convert the pressure sensor output into a digital signal;

a transmitter configured to transmit the digital signal to an external base unit; and

a power control unit configured to transition the in vivo sensor assembly from an inactive mode to an active mode having an active measurement interval at a predetermined frequency and to dynamically allocate power throughout the implantable sensor assembly, each of the pressure sensor, the signal conditioning component, and the transmitter having a necessary power interval during the active measurement interval with the power allocated by the power control unit such that during the active measurement interval, each of the pressure sensor, the signal conditioning component, and the transmitter are powered only for the associated necessary power interval to perform a related function, the necessary power interval being less than all of the active measurement interval, such that each of the signal conditioning component, and the transmitter are not powered for at least part of the active measurement interval.

2. The in vivo sensor assembly of claim 1 , wherein the active measurement interval has a duration of approximately one millisecond, and the predetermined frequency is between twenty and one hundred hertz.

3. The in vivo sensor assembly of claim 1 , wherein the signal conditioning component comprises an offset removal component configured to calculate a correction value for the output of the pressure sensor as a function of an average of a predetermined number of previous samples.

4. The in vivo sensor assembly of claim 3 , wherein the offset removal component calculates the correction value as a difference between the a full-scale range of a digital-to-analog converter associated with the transmitter and an average of a predetermined number of previous samples to maximize a sensing dynamic range of the in vivo sensor assembly.

5. The in vivo sensor assembly of claim 3 , wherein the signal conditioning component comprises an offset removal component responsive to an external command, the offset removal component being configured to, in response to the external command, instruct the sensor to take a plurality of measurements over a short period of time, the signal offset component calculating a correction value as an average of the plurality of measurements as to null the system.

6. The in vivo sensor assembly of claim 1 , wherein each of the signal conditioning component, the transmitter, and the power control unit are implemented as a single application-specific integrated circuit chip.

7. The in vivo sensor assembly of claim 1 , wherein the transmitter is powered during a portion of the active measurement interval for which neither of the signal conditioning component nor the pressure sensor is powered.

8. The in vivo sensor assembly of claim 7 , wherein the signal conditioning component is powered during a portion of the active measurement interval for which the pressure sensor is not powered.

9. An in vivo sensor assembly comprising:

a pressure sensor configured to provide an analog signal representing pressure;

a signal conditioning component configured to convert the pressure sensor output into a digital signal;

a transmitter configured to transmit the digital signal to an external base unit; and

a power control unit configured to transition the in vivo sensor assembly from an inactive mode to an active mode having an active measurement interval at a predetermined frequency and to dynamically allocate power throughout the implantable sensor assembly, each of the pressure sensor, the signal conditioning component, and the transmitter having a necessary power interval during the active measurement interval with the power allocated by the power control unit such that during the active measurement interval, each of the pressure sensor, the signal conditioning component, and the transmitter are powered only for the associated necessary power interval necessary to perform a related function, the necessary power interval being less than all of the active measurement interval, such that each of the signal conditioning component, the pressure sensor, and the transmitter are not powered for at least part of the active measurement interval.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 16, 2014
From: DAMASER, MARGOT S.; FLETTER, PAUL C.; ZASZCZURYNSKI, PAUL J.
To: THE CLEVELAND CLINIC FOUNDATION
Reel/Frame 033745/0418 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 16, 2014
From: MAJERUS, STEVE; GARVERICK, STEVEN L.; KO, WEN H.
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 033745/0569 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 16, 2014
From: DAMASER, MARGOT S.; MAJERUS, STEVEN; FLETTER, PAUL C.; GARVERICK, STEVEN L.; KO, WEN H.; ZASZCZURYNSKI, PAUL J.
To: THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
Reel/Frame 033745/0680 →
Continuity (2)
Provisional Application 61643988 · May 8, 2012
Related Publication 20130303942A1 · Nov 14, 2013
Cited By (3)
US 12,186,084 US 12,426,817 US 12,426,818