IP Library Granted Patent US 10,227,628
Granted Patent B2
US 10,227,628 · App. 13/892,939 · Granted Mar 12, 2019

Device for detecting a fungal contamination

Inventors: Stephane Moularat (Lognes, FR); Yael Joblin (Sucy en Brie, FR); Enric Robine (Lagny sur Marne, FR)
Assignee: CENTRE SCIENTIFIQUE ET TECHNIQUE DU BATIMENT
C12Q1/04G01N33/0047G01N33/0075G01N33/56961G01N33/0031G01N2030/025G01N2030/085
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Quick Facts
Patent No.
US 10,227,628
App. No.
13/892,939
Granted
Mar 12, 2019
Kind
B2
Abstract

The present invention relates to a device for detecting a fungal contamination in an internal environment, to the use thereof and also to a method for detecting a fungal contamination in an internal environment using such a device.

Claims (24)

1. A device for detecting a fungal contamination based on the detection of target VOCs (volatile organic compounds) in an internal environment comprising:

a preconcentration module;

a separation module comprising a chromatographic microcolumn comprising an outlet; and

a detection module comprising a matrix of sensors

wherein the separation module further comprises a selector, said selector comprises a solenoid valve directly connected to the outlet of the chromatographic microcolumn and a programmable unit for controlling said solenoid valve, said programmable unit being preprogrammed such that the selector is configured to selectively direct portions of eluate corresponding to a retention time of each of the target VOCs from the chromatographic microcolumn to the detection module and discharges the rest of the eluate,

wherein the preconcentration module comprises a micro-preconcentrator consisting of a substrate plate on the surface of which are etched grooves which contain an adsorbent material, and

wherein the etched grooves have a length of from 3 to 10 cm, a width of from 200 to 1000 μm, a depth of from 200 to 1000 μm and a cross section of from 0.04 to 1 mm 2 .

2. The device as claimed in claim 1 , wherein the chromatographic microcolumn has a length between 1 and 50 m.

3. The device as claimed in claim 1 , wherein the matrix of sensors comprises at least one polymer having an affinity with target VOCs (volatile organic compounds) of fungal origin.

4. The device as claimed in claim 1 , wherein the target VOCs (volatile organic compounds) are selected from the group consisting of 1-octen-3-ol, 1,3-octadiene, methyl 2-ethylhexanoate, 2-methylfuran, 3-methylfuran, 3-methyl-1-butanol, 2-methyl-1-butanol, α-pinene, 2-heptene, dimethyl sulfide, 4-heptanone, 2(5H)-furanone, 3-heptanol, methoxybenzene and 2-ethylhexanol, and mixtures thereof.

5. The device as claimed in claim 1 , wherein the substrate plate has a surface area of from 5 to 20 cm 2 .

6. The device as claimed in claim 1 , wherein the cross section of the grooves has a rectangular, semicircular or circular shape.

7. The device as claimed in claim 1 , wherein the preconcentration module further comprise a second plate adhesively bonded to the surface of substrate plate with the etched grooves.

8. A method for detecting a fungal contamination in an internal environment which is implemented by the device as defined in claim 1 and which comprises:

taking a sample of VOCs from the environment;

separating the VOCs sampled; and

detecting the VOCs present.

9. A method for detecting a fungal contamination in an internal environment which is implemented by the device as defined in claim 1 and which comprises:

taking a sample of VOCs from the internal environment;

separating the VOCs sampled;

selecting target VOCs; and

detecting the target VOCs present.

10. The method as claimed in claim 9 , wherein the target VOCs are chosen from the group consisting of 1-octen-3-ol, 1,3-octadiene, methyl 2-ethylhexanoate, 2-methylfuran, 3-methylfuran, 3-methyl-1-butanol, 2-methyl-1-butanol, α-pinene, 2-heptene, dimethyl sulfide, 4-heptanone, 2(5H)-furanone, 3-heptanol, methoxybenzene and 2-ethylhexanol, and mixtures thereof.

11. The method as claimed in claim 9 , wherein the detecting of the target VOCs is carried out continuously.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2013
From: MOULARAT, STEPHANE; JOBLIN, YAEL; ROBINE, ENRIC
To: CENTRE SCIENTIFIQUE ET TECHNIQUE DU BATIMENT
Reel/Frame 031534/0894 →
Priority Claims (1)
FR 10 59636 · Nov 23, 2010 · national
Continuity (2)
Continuation In Part PCTFR2011052720 · Nov 22, 2011
Related Publication 20130323781A1 · Dec 5, 2013
Cited By (3)
US 12,251,991 US 12,269,315 US 12,377,711