Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)

1. A method of prolonging survival of a subject suffering from breast cancer, wherein said breast cancer is ER-positive and AR-positive metastatic breast cancer, ER-positive and AR-positive refractory breast cancer, ER-positive and AR-positive advanced breast cancer, and/or ER-positive and AR-positive breast cancer that has failed selective estrogen receptor modulator, aromatase inhibitor, and/or fulvestrant treatments; or said breast cancer is triple negative breast cancer; the method comprising administering to said subject a selective androgen receptor modulator (SARM) compound represented by a structure of formula IX:

2. The method of claim 1 , comprising administering an isomer, a racemic mixture containing a SARM compound, a metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or crystal of said selective androgen receptor modulator, or any combination thereof.

3. The method of claim 2 , wherein said administering comprises intravenously, intraarterially, or intramuscularly injecting to said subject said pharmaceutical product in liquid form; subcutaneously implanting in said subject a pellet containing said pharmaceutical product; orally administering to said subject said pharmaceutical product in a liquid or solid form; or topically applying to said subject said pharmaceutical product.

4. The method of claim 2 , wherein said pharmaceutical product is a pellet, a tablet, a capsule, a solution, a suspension, an emulsion, an elixir, a gel, a cream, a suppository or a parenteral formulation.