Compositions, gels and foams with rheology modulators and uses thereof
The present disclosure relates generally to compositions for cosmetic or pharmaceutical application. The compositions include a carrier and rheology modulators.
1. An oleaginous foam composition comprising:
a) a combination of at least one fatty alcohol and at least one wax; or a combination of at least one fatty alcohol, at least one fatty acid, and at least one wax;
b) at least one hydrophobic solvent; and
c) a minocycline at a concentration between about 1% and about 4% by weight of the composition;
wherein the composition is free of surfactant;
wherein the composition is essentially waterless;
wherein the ratio of (1) fatty alcohol to wax or (2) fatty alcohol and fatty acid to wax is between about 1:3 and about 3:1; and
wherein the wax comprises a mixture of beeswax and hydrogenated castor oil.
2. The composition of claim 1 , wherein the minocycline is present in a free base form, a hydrate form, a salt form, or a complex form.
3. The composition of claim 1 , further comprising a tetracycline, an oxytetracycline, a demeclocycline, a doxycycline, a lymecycline, a meclocycline, a methacycline, a rolitetracycline, a chlorotetracycline, a tigecycline, or a mixture of two or more thereof.
4. The composition of claim 1 , further comprising a doxycycline.
5. The composition of claim 1 , wherein the concentration of the minocycline is about 4% by weight of the composition.
6. The composition of claim 1 , wherein the concentration of the minocycline is about 1% by weight of the composition.
7. The composition of claim 1 , wherein the at least one fatty alcohol comprises 14 carbon atoms in its backbone.
8. The composition of claim 1 , wherein the fatty alcohol comprises stearyl alcohol, cetostearyl alcohol, behenyl alcohol, and/or myristyl alcohol.
9. The composition of claim 1 , wherein the at least one fatty alcohol is present at a concentration from about 0.1% to about 20% by weight of the composition.
10. The composition of claim 1 , wherein the at least one wax and/or the at least one fatty acid is present at a concentration from about 0.1% to about 20% by weight of the composition.
11. The composition of claim 1 , wherein the hydrophobic solvent comprises soybean oil, coconut oil, cyclomethicone, and/or mineral oil.
12. The composition of claim 1 , wherein the hydrophobic solvent is present at a concentration from about 60% to about 95% by weight of the composition.
13. The composition of claim 1 , further comprising a retinoid.
14. The composition of claim 13 , wherein the retinoid comprises tazarotene, adapalene, and/or isotretinoin.
15. The composition of claim 1 , further comprising a silicon dioxide.
16. The composition of claim 1 , further comprising a benzoyl peroxide.
17. The composition of claim 1 , wherein the wax comprises a mixture of beeswax and hydrogenated castor oil at a ratio of about 1:1.
18. The composition of claim 1 , wherein the concentration of the minocycline is about 3% by weight of the composition.