IP Library › Granted Patent US 10,280,133
Granted Patent B2
US 10,280,133 · App. 16/028,592 · Granted May 7, 2019

Process for the manufacture of 4-aminobenzoamidine dihydrochloride

Inventors: Weitong Dong (Pudong District, CN); Christian Wolfgang Hemp (Mainz, DE); Xiangle Jin (Pudong District, CN); Jun Lu (Pudong District, CN); Ulrich Scholz (Bad Kreuznach, DE); Shengmin Su (Shanghai, CN); Wei Xu (Pudong District, CN); Jinsong Yang (Pudong District, CN)
Assignee: Boehringer Ingelheim International GmbH
C07C213/00C07C217/76C07C249/02C07C257/08C07C257/18
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Quick Facts
Patent No.
US 10,280,133
App. No.
16/028,592
Granted
May 7, 2019
Kind
B2
Abstract

The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.

Claims (2)

1. A compound of formula (II),

wherein R is methyl and X is Cl.

Priority Claims (1)
WO PCT/CN2012/083317 · Oct 22, 2012 · international
Continuity (3)
Division 15190756 · Jun 23, 2016
Division 14055054 · Oct 16, 2013
Related Publication 20180319735A1 · Nov 8, 2018