Packaged medicine-filled container
A packaged medicine-filled container has a resin-made medicine-filled container in which a medicine is housed, a sealed packaging body in which the medicine-filled container is housed, and an oxygen scavenger housed inside the packaging body. The packaging body is hardly oxygen-permeable. Both a moisture-dependent type oxygen scavenger and a self-reacting type oxygen scavenger are used as the oxygen scavenger.
1. A composition comprising:
a prefilled syringe comprising:
an outer cylinder formed of a resin having low water vapor permeability, the resin comprising polypropylene or cyclic polyolefin, the outer cylinder comprising a nozzle,
a medicine housed in said outer cylinder,
a gasket housed in said outer cylinder and slidable inside said outer cylinder, said gasket being formed of an elastic material having low water vapor permeability,
a sealing member for sealing said nozzle of said outer cylinder, the sealing member being formed of a material having low water vapor permeability,
wherein the prefilled syringe, in its entirety, has low water vapor permeability;
a sealed packaging body in which said prefilled syringe is housed, wherein said packaging body has low oxygen permeability;
a moisture-dependent type oxygen scavenger housed inside said packaging body; and
a self-reacting type oxygen scavenger housed inside said packaging body.
2. The composition according to claim 1 , wherein said moisture-dependent type oxygen scavenger is an iron-based moisture-dependent type oxygen scavenger.
3. The composition according to claim 1 , wherein said self-reacting type oxygen scavenger is an iron-based self-reacting type oxygen scavenger or an organic self-reacting type oxygen scavenger.
4. The composition according to claim 1 , wherein said packaging body has a tray having an opening and a container body housing part and a sealing sheet for sealing said opening of said tray.
5. The composition according to claim 4 , wherein said moisture-dependent type oxygen scavenger and said self-reacting type oxygen scavenger are housed at a bottom part inside said tray.
6. The composition according to claim 1 , wherein said moisture-dependent type oxygen scavenger and said self-reacting type oxygen scavenger are apart from each other.
7. The composition according to claim 5 , wherein a lower surface of said moisture-dependent type oxygen scavenger and a lower surface of said self-reacting type oxygen scavenger are fixed to an inner bottom surface of said tray.
8. The composition according to claim 1 , wherein said prefilled syringe has a contact portion between the gasket and the outer cylinder, and water vapor is permeable to a low extent at said contact portion between the gasket and the outer cylinder.