IP Library Granted Patent US 10,330,764
Granted Patent B2
US 10,330,764 · App. 15/287,114 · Granted Jun 25, 2019

Magnetic resonance measuring apparatus and image processing method

Inventor: Yoshitaka Bito (Tokyo, JP)
Assignee: HITACHI, LTD.
G01R33/56509G01R33/4625
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Quick Facts
Patent No.
US 10,330,764
App. No.
15/287,114
Granted
Jun 25, 2019
Kind
B2
Abstract

Provided is a magnetic resonance measuring apparatus that records measurement data measured by MRS or the like and a periodic motion of the measurement object during the measurement of the measurement data in association with each other, and classifies spectra calculated from the measurement data in accordance with a time phase of the periodic motion. Created spectra are integrated for each classification to thereby create partially integrated spectra, correction based on a relationship between the periodic motion and a phase fluctuation or a frequency fluctuation is performed on the partially integrated spectra, and the corrected partially integrated spectra are synthesized.

Claims (58)

1. A magnetic resonance measuring apparatus comprising:

a measurement unit that measures nuclear magnetic resonance signals emitted from an inspection object;

a computational calculation unit that calculates spectrum information corresponding to molecules or nuclei included in the inspection object, by using the nuclear magnetic resonance signals measured by the measurement unit; and

a body motion information recording unit that records measurement signals, measured by the measurement unit, in association with body motion signals indicating periodic movement of the inspection object during the measurement of the measurement signals,

wherein the computational calculation unit includes

a spectrum calculation unit that calculates spectra based on the nuclear magnetic resonance signals,

a correction unit that corrects the measurement signals or the spectra, on the basis of a relationship between the periodic movement and a phase fluctuation and/or a frequency fluctuation of the spectra,

a synthesis unit that synthesizes the measurement signals or the spectra corrected by the correction unit,

a classification unit that classifies the measurement signals or the spectra in accordance with the body motion signals during the measurement of the measurement signals, and

a partially integrating unit that integrates the measurement signals or the spectra classified by the classification unit, for each classification group, and

wherein the correction unit corrects phases and/or frequencies with respect to each spectrum calculated from integrated measurement signals or spectra, integrated by the partially integrating unit.

2. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the computational calculation unit calculates a time phase relational expression between the periodic movement and the phase fluctuation and/or the frequency fluctuation of the spectra, and

wherein the correction unit corrects the spectra using the time phase relational expression.

3. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the body motion information recording unit records a signal applied from a body motion detection apparatus mounted to the inspection object as a body motion signal.

4. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the measurement unit measures a navigation echo, apart from a measurement signal for obtaining the spectrum information, and

wherein the computational calculation unit detects body motion information using the navigation echo, and transmits the detected body motion information to the body motion information recording unit.

5. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the body motion information recording unit records a body motion signal of a breathing motion or a heartbeat as the periodic movement.

6. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the measurement unit performs first measurement in which a signal from a water proton is not suppressed, and second measurement in which a signal from a water proton is suppressed, and

wherein the correction unit calculates a correction value for correcting the spectra by using measurement data obtained by the first measurement, and performs correction on measurement data obtained by the second measurement by using the correction value.

7. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the measurement unit measures nuclear magnetic resonance signals from one or more regions of the inspection object, and

wherein the computational calculation unit calculates metabolite spectra of the or more regions.

8. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the measurement unit measures nuclear magnetic resonance signals from a plurality of regions included in a cross section of the inspection object, and

wherein the computational calculation unit creates metabolite distribution of the cross section.

9. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the measurement unit applies an MPG pulse to the inspection object in one or more predetermined directions to thereby measure the nuclear magnetic resonance signals from one or more regions, and

wherein the computational calculation unit calculates diffusion-weighted spectra of metabolites included in the one or more regions.

10. The magnetic resonance measuring apparatus according to claim 1 ,

wherein the measurement unit applies an MPG pulse to the inspection object in one or more predetermined directions to thereby measure the nuclear magnetic resonance signals from a plurality of regions included in a cross section of the inspection object, and

wherein the computational calculation unit creates spatial distribution of molecular diffusion of metabolites included in the cross section.

11. The magnetic resonance measuring apparatus according to claim 1 , wherein the computational calculation unit synthesizes each corrected partially integrated spectrum amongst the one or more spectra corrected by the correction unit, into a synthesized spectrum.

12. An image processing method of generating a spectrum or a spectroscopic image of a measurement object by using measurement data measured by a magnetic resonance measuring apparatus, the image processing method comprising:

(a) recording measurement data in association with a periodic motion of the measurement object during the measurement of the measurement data;

(b) correcting at least one of a phase fluctuation and a frequency fluctuation included in the measurement data on the basis of a relationship between the periodic motion and the phase fluctuation or the frequency fluctuation;

(c) calculating a spectrum by using the corrected measurement data;

(c1) classifying the measurement data or spectra in accordance with the periodic motion during the measurement of the measurement data;

(c2) integrating the measurement data or the spectra classified in (c1), for each classification group; and

(c3) correcting phases and/or frequencies with respect to each spectrum calculated from integrated measurement signals or spectra, integrated in (c2).

13. An image processing method of generating a spectrum or a spectroscopic image of a measurement object by using measurement data measured by a magnetic resonance measuring apparatus, the image processing method comprising:

(a) recording measurement data in association with a periodic motion of the measurement object during the measurement of the measurement data;

(b) correcting at least one of a phase fluctuation and a frequency fluctuation included in spectra calculated from the measurement data, on the basis of a relationship between the periodic motion and the phase fluctuation or the frequency fluctuation;

(c1) classifying the measurement data or the spectra in accordance with the periodic motion during the measurement of the measurement data;

(c2) integrating the measurement data or the spectra classified in (c1), for each classification group; and

(c3) correcting phases and/or frequencies with respect to each spectrum calculated from integrated measurement data or spectra, integrated in (c2).

14. The image processing method according to claim 13 , further comprising:

classifying the spectra calculated from the measurement data in accordance with a time phase of the periodic motion;

integrating the classified spectra for each classification to thereby create partially integrated spectra;

performing correction based on the relationship between the periodic motion and the phase fluctuation or the frequency fluctuation on the partially integrated spectra; and

synthesizing the corrected partially integrated spectra.

15. The image processing method according to claim 13 , further comprising:

calculating a relational expression between at least one of a phase fluctuation and a frequency fluctuation included in the spectrum and a time phase of the periodic motion; and

correcting at least one of the phase fluctuation and the frequency fluctuation in accordance with the relational expression.

Assignments (5)
MERGER Recorded Jan 10, 2025
From: FUJIFILM HEALTHCARE CORPORATION
To: FUJIFILM CORPORATION
Reel/Frame 069869/0916 →
MERGER Recorded Oct 11, 2024
From: FUJIFILM HEALTHCARE CORPORATION
To: FUJIFILM CORPORATION
Reel/Frame 070607/0754 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE PROPERTY AND APPLICATION NUMBERS PREVIOUSLY RECORDED AT REEL: 058026 FRAME: 0559. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 31, 2022
From: HITACHI LTD.
To: FUJIFILM HEALTHCARE CORPORATION
Reel/Frame 058917/0853 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2021
From: HITACHI, LTD.
To: FUJIFILM HEALTHCARE CORPORATION
Reel/Frame 058026/0559 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 6, 2016
From: BITO, YOSHITAKA
To: HITACHI, LTD.
Reel/Frame 040249/0796 →
Priority Claims (1)
JP 2016-169508 · Aug 31, 2016 · national
Continuity (1)
Related Publication 20180059202A1 · Mar 1, 2018