IP Library Granted Patent US 10,420,522
Granted Patent B2
US 10,420,522 · App. 15/428,729 · Granted Sep 24, 2019

Generating contrast-enhanced image data based on multi-energy X-ray imaging

Inventors: Thomas Flohr (Uehlfeld, DE); Bernhard Schmidt (Fuerth, DE)
Assignee: SIEMENS HEALTHCARE GMBH
A61B6/481A61B6/032A61B6/405A61B6/4007A61B6/4014A61B6/4241A61B6/482A61B6/5205A61B6/504A61B6/507
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Quick Facts
Patent No.
US 10,420,522
App. No.
15/428,729
Granted
Sep 24, 2019
Kind
B2
Abstract

An X-ray imaging method is for generating contrast-enhanced image data relating to an examination region of an object to be examined. In an embodiment of the method, first contrast-agent influenced measured X-ray projection data with a first X-ray energy spectrum and at least one set of second contrast-agent influenced measured X-ray projection data with a second X-ray energy spectrum are acquired from the examination region. Subsequently, image data assigned to a third X-ray energy spectrum with a third mean energy, based on the first and at least second measured X-ray projection data is reconstructed based on the first and at least second measured X-ray projection data that has been acquired. A mean energy of the first X-ray energy spectrum and a mean energy of the second X-ray energy spectrum are selected as a function of a dimension parameter value of the object that is to be examined.

Claims (42)

1. An X-ray imaging method for generating contrast-enhanced image data of an examination region of an object to be examined, comprising:

acquiring first contrast-agent influenced measured X-ray projection data using a first X-ray energy spectrum and at least second contrast-agent influenced measured X-ray projection data using a second X-ray energy spectrum from the examination region; and

reconstructing pseudo-monoenergetic image data to generate the contrast-enhanced image data of the examination region of the object, the pseudo-monoenergetic image data assigned to a third X-ray energy spectrum with a third mean energy, the third X-ray energy spectrum based on the acquired first and at least second measured X-ray projection data, wherein

a mean X-ray energy of the first X-ray energy spectrum and a mean X-ray energy of the at least second X-ray energy spectrum are selected as a function of a dimension parameter value of the object to be examined.

2. The X-ray imaging method of claim 1 , wherein,

the mean energy of the first X-ray energy spectrum and the mean energy of the second X-ray energy spectrum correspond to a first image noise, and the mean energy of the third X-ray energy spectrum corresponds to a second image noise, the first image noise being less than the second image noise,

the mean energy of the first X-ray energy spectrum and the mean energy of the second X-ray energy spectrum are both higher than the mean energy of the third X-ray energy spectrum, or

the mean energy of the first X-ray energy spectrum and the mean energy of the second X-ray energy spectrum correspond to a first image noise, the mean energy of the third X-ray energy spectrum corresponds to a second image noise, the first image noise being less than the second image noise, and the mean energy of the first X-ray energy spectrum and the mean energy of the second X-ray energy spectrum are both higher than the mean energy of the third X-ray energy spectrum.

3. The X-ray imaging method of claim 1 , wherein the X-ray imaging method includes a dynamic time-resolved imaging method.

4. The X-ray imaging method of claim 1 , wherein an X-ray energy distribution around the mean X-ray energy of the third X-ray energy is used as a third X-ray energy spectrum, and wherein at the mean X-ray energy of the third X-ray energy, there is an increased contrast/noise ratio in the image data to be generated.

5. The X-ray imaging method of claim 1 , wherein the third X-ray energy spectrum includes a distribution around a mean X-ray energy, the mean X-ray energy being near to an X-ray absorption edge of the contrast agent that is used for contrast enhancement.

6. The X-ray imaging method of claim 1 , wherein the contrast agent includes iodine, and the third X-ray energy spectrum has a mean energy between 35 keV and 60 keV.

7. The X-ray imaging method of claim 1 , wherein the dimension parameter value includes information relating to one of

a body mass of the object to be examined,

the dimensions of the the object to be examined,

a body-mass index (BMI) of the object to be examined,

a sub-combination thereof, or a combination thereof.

8. The X-ray imaging method of claim 1 , wherein

the acquiring includes using a multi-source CT system,

wherein the first X-ray projection data is acquired simultaneously with the at least second measured X-ray projection data.

9. The X-ray imaging method of claim 1 , wherein

the acquiring includes using a single-source CT system with a single X-ray tube, and wherein the X-ray tube performs a rapid switchover of an electric voltage to acquire the first and at least second measured X-ray projection data.

10. The X-ray imaging method of claim 1 , wherein the acquiring includes using a photon-counting X-ray detector.

11. The X-ray imaging method of claim 1 , wherein the acquiring further includes:

acquiring additional image data at a fourth X-ray energy with a high mean energy, based on the first and at least second measured X-ray projection data, and wherein,

the additional image data corresponds to image data that is not contrast-enhanced,

the reconstructing pseudo-monoenergetic image data includes using a filtering method to reduce image noise, or

both the additional image data corresponds to image data that is not contrast-enhanced and the reconstructing pseudo-monoenergetic image data includes using a filtering method to reduce image noise.

12. An image data reconstruction device, comprising:

an X-ray energy-determination unit configured to determine a mean energy of a first X-ray energy spectrum and a mean energy of at least a second X-ray energy spectrum as a function of a dimension parameter value relating to an object to be examined;

a control unit configured to activate one or more of a plurality of X-ray sources in a CT system such that the one or more of the plurality of X-ray sources generates X-ray radiation respectively using each of the first X-ray energy spectrum and the at least second X-ray energy spectrum with the respectively determined first and at least second mean energy values;

a measured projection data acquisition unit configured to acquire a first contrast-agent influenced measured X-ray projection data using the first X-ray energy spectrum and an at least second contrast-agent influenced measured X-ray projection data using the at least second X-ray energy spectrum, relating to an examination region in the examination object; and

an image data reconstruction unit to reconstruct pseudo-monoenergetic image data, assigned to a third X-ray energy spectrum, based on the acquired first and at least second measured X-ray projection data.

13. A computer tomography system, comprising the image data generating device of claim 12 .

14. A non-transitory computer program product, including a computer program, directly loadable into a memory unit of an image data generating device, including program segments to carry out the method of claim 1 when the computer program is run in the image data generating device.

15. A non-transitory computer-readable medium, including transferable and executable program segments of a computer program, stored by a processor unit of an image data generating device, to carry out the method of claim 1 when the program segments are run by the processor unit of the image data generating device.

16. The X-ray imaging method of claim 1 , wherein the X-ray imaging method includes a CT X-ray imaging method.

17. The X-ray imaging method of claim 3 , wherein the dynamic time-resolved imaging method includes a CT angiography method or a CT perfusion imaging method.

18. The X-ray imaging method of claim 2 , wherein the X-ray imaging method includes a dynamic time-resolved imaging method.

19. The X-ray imaging method of claim 18 , wherein the dynamic time-resolved imaging method includes a CT angiography method or a CT perfusion imaging method.

20. The X-ray imaging method of claim 2 , wherein the third X-ray energy spectrum includes an X-ray energy distribution around a third mean X-ray energy, and wherein at the third mean X-ray energy, a contrast/noise ratio in the image data to be generated is greater than a contrast/noise ratio in the image data.

21. The X-ray imaging method of claim 6 , wherein the third X-ray energy spectrum has a mean energy between 40 keV and 45 keV.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066267/0346 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 9, 2017
From: FLOHR, THOMAS; SCHMIDT, BERNHARD
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 042657/0470 →
Priority Claims (1)
DE 10 2016 203 257 · Feb 29, 2016 · national
Continuity (1)
Related Publication 20170245816A1 · Aug 31, 2017