IP Library Granted Patent US 10,429,401
Granted Patent B2
US 10,429,401 · App. 14/804,214 · Granted Oct 1, 2019

Methods and systems for tube inspection and liquid level detection

Inventors: Sebastian Streibl (Munich, DE); Jiuliu Lu (Palmetto Bay, FL); Bian Qian (Weston, FL); Melvin Ayala (Hollywood, FL)
Assignee: Beckman Coulter, Inc.
G01N35/00584G01F23/00G01N33/49G01N35/00732G01N35/1016G01N2035/1025
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Quick Facts
Patent No.
US 10,429,401
App. No.
14/804,214
Granted
Oct 1, 2019
Kind
B2
Abstract

Container identification data from a container inspection unit that analyzes a container containing a liquid is combined with liquid level detection raw data from a liquid level detection unit that analyzes the container containing the liquid and a liquid level detection result is generated. The liquid level detection result is cross-checked with additional data from the container inspection unit. The result can be used to plan a route for the container in the laboratory automation system.

Claims (45)

1. A method comprising:

receiving, by a processor, container identification data from a container inspection unit that analyzes a container containing a liquid;

determining, by a liquid level detection unit, liquid level detection raw data including a height of a liquid content layer within the container by rotating the container about a z-axis of the container as the container is held by a robotic arm, and obtaining multiple angular readings of the liquid around the container;

receiving, by the processor, the liquid level detection raw data from the liquid level detection unit that analyzes the container containing the liquid;

determining a liquid level detection result for the liquid in the container, based at least on the container identification data and the liquid level detection raw data;

receiving, by the processor, additional data from the container inspection unit;

cross-checking, by the processor, the liquid level detection result with the additional data received from the container inspection unit; and

determining if the liquid level detection result is erroneous as a result of the cross-checking.

2. The method of claim 1 further comprising:

generating, by the processor, a combined result of the container inspection unit and the liquid level detection unit after cross-checking the liquid level detection result.

3. The method of claim 2 wherein the combined result includes volume information, content confirmation, liquid layers, a gel position, a spun state, a serum/cruor ratio and error states.

4. The method of claim 1 wherein the container is a tube comprising a cap, and the container inspection unit is a tube inspection unit.

5. The method of claim 1 wherein the liquid level detection unit executes one or more of a serum/urine detection algorithm, a gel detection algorithm, a cruor detection algorithm and a whole blood detection algorithm.

6. The method claim 1 wherein the liquid level detection unit comprises a device that measures the height of the liquid content layer in the container by transmitting radiation through the container.

7. The method of claim 1 wherein the container inspection unit comprises a camera.

8. The method of claim 1 the liquid level detection result includes a liquid level and a sample volume.

9. The method of claim 1 wherein the container identification data comprises one or more of an inner diameter, an outer diameter, a height, a height without cap, a color pattern side, a color pattern top, a top rubber (inner) diameter, a decapping profile, a liquid level height offset, a “calculate no volume” flag, a cap material type, a “tube has thread” flag, a “cap pierce through” flag, a “contains gel” flag, a bottom shape, an expected gel height, a sample type, a false bottom (inlay), a conicity/tapering flag, a translucent flag, or a draw volume of the container.

10. The method of claim 1 , wherein the liquid contains serum and gel, and wherein an interface between the serum and the gel is at an angle relative to a vertical axis of the container.

11. The method of claim 1 , wherein the multiple angular readings of the liquid around the container are obtained using multiple pairs of light sources and light detectors.

12. The method of claim 1 wherein the robotic arm has at least three prongs which grip the container.

13. The method of claim 1 wherein the container is vertical as it is rotated.

14. The method of claim 1 wherein the multiple angular readings is ten angular readings.

15. A computer comprising:

a processor; and

a computer readable medium coupled to the processor, the computer readable medium comprising code, executable by the processor, to implement a method comprising:

receiving container identification data from a container inspection unit that analyzes a container containing a liquid;

determining, by a liquid level detection unit, liquid level detection raw data including a height of a liquid content layer within the container by rotating the container about a z-axis of the container as the container is held by a robotic arm, and obtaining multiple angular readings of the liquid around the container;

receiving the liquid level detection raw data from the liquid level detection unit that analyzes the container containing the liquid;

determining a liquid level detection result for the liquid in the container, based at least on the container identification data and the liquid level detection raw data;

receiving, by the processor, additional data from the container inspection unit;

cross-checking, by the processor, the liquid level detection result with the additional data received from the container inspection unit; and

determining if the liquid level detection result is erroneous as a result of the cross-checking.

16. The computer of claim 15 wherein the method further comprises:

generating a combined result of the container inspection unit and the liquid level detection unit after cross-checking the liquid level detection result.

17. The computer of claim 15 wherein the liquid level detection unit executes one or more of a serum/urine detection algorithm, a gel detection algorithm, a cruor detection algorithm and a whole blood detection algorithm.

18. A system comprising:

the computer of claim 15 ;

the container inspection unit coupled to the computer; and

the liquid level detection unit coupled to the computer.

19. The system of claim 18 wherein the method further comprises

generating a combined result of the container inspection unit and the liquid level detection unit after cross-checking the liquid level detection result.

20. The system of claim 19 wherein the method further comprises:

distributing the combined result to one or more additional units coupled to the computer.

21. The system of claim 20 wherein the additional units include a centrifuge unit, a decapper unit, a recapper unit, an aliquotter unit, an analyzer unit and an output unit.

22. The system of claim 19 wherein the combined result includes a volume, content confirmation, layers of the liquid, a gel position, a spun state, a serum/cruor ratio, a container identifier, a cap identifier, a cap color identifier and error states.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 13, 2019
From: STREIBL, SEBASTIAN; LU, JIULIU; QIAN, BIAN; AYALA, MELVIN
To: BECKMAN COULTER, INC.
Reel/Frame 049463/0827 →
Continuity (2)
Provisional Application 62027044 · Jul 21, 2014
Related Publication 20160018427A1 · Jan 21, 2016
Cited By (3)
US 12,405,284 US 12,442,830 US 12,699,109