Imidazo[4,5-b]pyridin-2-yl amides as Kv7 channel activators

Inventors: Lynn Resnick (Pittsburgh, PA); George T. Topalov (Pittsburgh, PA); Charles A. Flentge (Mars, PA); James S. Hale (Pittsburgh, PA); David A. Mareska (McMurray, PA); Justin K. Belardi (Pittsburgh, PA); Kai Zhang (Wexford, PA); Scott S. Harried (Sun Prairie, WI)

Assignee: Knopp Biosciences LLC

C07D471/04 C07D519/00

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Quick Facts

Patent No.: US 10,526,328
App. No.: 16/124,853
Granted: Jan 7, 2020
Kind: B2

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Abstract

Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.

Claims (1)

1. A compound represented by a formula:

Assignments (12)

RELEASE OF SECURITY INTEREST Recorded Apr 12, 2022

From: AMERICAN MONEY MANAGEMENT CORPORATION

To: KNOPP BIOSCIENCES LLC

Reel/Frame 059572/0530 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2022

From: CHANNEL BIOSCIENCES, LLC

To: BIOHAVEN THERAPEUTICS LTD.

Reel/Frame 059598/0607 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2022

From: KNOPP BIOSCIENCES LLC

To: CHANNEL BIOSCIENCES, LLC

Reel/Frame 059681/0638 →

SECURITY INTEREST Recorded Apr 12, 2021

From: KNOPP BIOSCIENCES LLC

To: AMERICAN MONEY MANAGEMENT CORPORATION

Reel/Frame 055889/0064 →