IP Library Granted Patent US 10,532,017
Granted Patent B2
US 10,532,017 · App. 15/779,272 · Granted Jan 14, 2020

Stable antioxidant compositions

Inventors: Lisa Yarhyna Lema (Bronx, NY); Valerie Robert (Paris, FR); Jodi Goldberg (Springfield, NJ); Geoffrey Genesky (Paris, FR)
Assignee: L'OREAL
A61K8/60A61K8/06A61K8/342A61K8/345A61K8/365A61K8/678A61K8/737A61K8/92A61Q19/08A61K2800/48A61K2800/522
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Quick Facts
Patent No.
US 10,532,017
App. No.
15/779,272
Granted
Jan 14, 2020
Kind
B2
Abstract

The present disclosure relates to antioxidant compositions comprising a high amount of stabilized neohesperidin dihydrochalcone. The antioxidant compositions may further include additional antioxidants, such as ferulic acid, and tocopherols. The compositions include at least 20 wt. % of one or more water-soluble solvents, such as propanediol, which contribute to the surprising solubility and stability of the compositions. The antioxidant properties of the compositions make them particularly effective for treating and protecting the skin. For example, the compositions are useful for protecting the skin from environmental insult.

Claims (47)

1. A topical antioxidant composition comprising:

(a) at least 0.5 to 3 wt. % of neohesperidin dihydrochalcone;

(b) about 1 wt. % to about 30 wt. % by weight of one or more of fatty compounds;

(c) about 0.1 wt. % to about 2 wt. % by weight of one or more natural thickeners;

(d) at least 20 wt. % 1,3-propanediol;

(e) about 1 wt. % to about 15 wt. % by weight of one or more emulsifiers;

(f) optionally, one or more natural active compounds; and

(g) water;

wherein the composition is in the form of an emulsion,

the composition does not exhibit phase separation and/or visible crystallization for at least two months at a temperature of about 25° C.; and

all percentages by weight are based on the total weight of the composition.

2. The antioxidant composition of claim 1 comprising about 0.9 wt. % to about 1.1 wt. % of neohesperidin dihydrochalcone.

3. The antioxidant composition of claim 1 , further comprising ferulic acid.

4. The antioxidant composition of claim 1 , further comprising tocopherols.

5. The antioxidant composition of claim 1 , further comprising ferulic acid and tocopherols.

6. The antioxidant composition of claim 5 , wherein the total amount of the neohesperidin dihydrochalcone, ferulic acid, and tocopherols in the compositions is from about 1% to about 5%.

7. The antioxidant composition of claim 6 comprising about 0.9 wt. % to about 1.1 wt. % of neohesperidin dihydrochalcone.

8. The antioxidant composition of claim 1 ,

wherein the one or more fatty compounds are selected from the group consisting of natural oils of vegetable, animal or marine origin, synthetic oils, mineral oils, hydrogenated oils, silicone oils, hydrocarbon-based compounds, saturated or unsaturated fatty acids, fatty acid esters, liquid waxes, fatty alcohols, and a mixture thereof.

9. The antioxidant composition of claim 8 comprising one or more vegetable oils.

10. The antioxidant composition of claim 1 , further comprising 1,2-octanediol.

11. The antioxidant composition of claim 1 comprising glycerin.

12. The antioxidant composition of claim 1 , wherein the one or more natural thickeners comprises one or more polysaccharide thickeners.

13. The antioxidant composition of claim 12 , wherein the one or more polysaccharide thickeners is selected from the group consisting of gellan gum, xanthan gum, rhamsan gum, welan gum, carrageenan, guar gum, locust bean gum, tragacanth gum, succinoglucan gum, and mixtures thereof.

14. The antioxidant composition of claim 1 comprising one or more emulsifiers selected from the group consisting of stearic acid, cetyl alcohol, PEG-100 stearate and glyceryl stearate, cetearyl glucoside, polysorbate 20, ceteareth-20, cetyl alcohol, cetearyl alcohol, cetyl palmitate, stearyl alcohol, lecithin, hydrogenated lecithin, steareth-2, steareth-20, polyglyceryl-2 stearate, and mixtures thereof.

15. The composition of claim 1 , further comprising caprylyl glycol and glycerin.

16. A topical antioxidant composition comprising:

(a) about 0.9 wt. % to about 1.1 wt. % of neohesperidin dihydrochalcone;

(b) about 1 wt. % to about 30 wt. % by weight of one or more of fatty compounds;

(c) about 0.1 wt. % to about 2 wt. % by weight of one or more natural thickeners;

(d) at least 20 wt. % of 1,3-propanediol;

(e) about 5 wt. % to about 15 wt. % of one or more emulsifiers;

(f) optionally, one or more natural active compounds; and

(g) water,

wherein the composition is in the form of an emulsion,

the composition does not exhibit phase separation and/or visible crystallization for at least two months at a temperature of about 25° C.; and

all percentages by weight are based on the total weight of the composition.

17. The antioxidant composition of claim 16 , further comprising ferulic acid and tocopherols.

18. The composition of claim 16 , further comprising caprylyl glycol and glycerin.

19. A method for treating skin conditions resulting from environmental stress and pollution comprising topically applying to the skin area in need of the treatment an antioxidant composition of claim 1 .

20. A method for:

(a) improving the radiance of skin;

(b) improving the evenness of skin tone;

(c) improving the clarity of skin; and/or

(d) improving the overall appearance of skin:

comprising applying an antioxidant composition of claim 1 to the skin.

21. The method of claim 20 , wherein the skin is facial skin.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 19, 2018
From: LEMA, LISA YARHYNA; ROBERT, VALERIE; GOLDBERG, JODI; GENESKY, GEOFFREY
To: L'OREAL
Reel/Frame 047536/0976 →
Continuity (3)
Provisional Application 62272326 · Dec 29, 2015
Provisional Application 62272291 · Dec 29, 2015
Related Publication 20180325792A1 · Nov 15, 2018
Cited By (1)
US 12,390,444