Methods for treating idiopathic pulmonary fibrosis
The present invention relates to methods and medicaments useful for treating idiopathic pulmonary fibrosis (IPF) by administering anti-CTGF antibodies. Methods for prognosing individuals with IPF are also provided.
1. A method for increasing forced vital capacity percent predicted (FVC % predicted) in a subject with idiopathic pulmonary fibrosis (IPF), the method comprising administering at least 30 mg/kg of an anti-connective tissue growth factor (CTGF) antibody that has the same amino acid sequence as the antibody produced by the cell line identified by ATCC Accession No. PTA-6006, thereby increasing the subject's FVC % predicted.
2. The method of claim 1 , further comprising the administration of an additional therapeutic agent selected from the group consisting of pirfenidone, nintedanib, corticosteroids, antibiotics, immunosuppressive drugs and supplemental oxygen.