IP Library Granted Patent US 10,596,309
Granted Patent B2
US 10,596,309 · App. 15/305,675 · Granted Mar 24, 2020

Hemodialysis system

Inventors: Pierre Thiebaud (Cressier, CH); Frédéric Neftel (Crans-Montana, CH)
Assignee: NextKidney SA
A61M1/1696A61M1/1601A61M1/1629A61M1/1682A61M1/1692A61M1/287A61M1/3472A61M2205/3331A61M2205/3337A61M2205/3368A61M2205/3393B01D61/30B01D2313/243
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Quick Facts
Patent No.
US 10,596,309
App. No.
15/305,675
Granted
Mar 24, 2020
Kind
B2
Abstract

A dialysis system comprises a filtration means, a pump and a sorbent device for performing a dialysis treatment and/or for regenerating a dialysate solution.

Claims (56)

1. A blood purification system comprising:

a dialysate circuit forming a loop circuit including a mixing bag, a dialyzer, and a sorbent device;

a pumping device positioned in the loop circuit; and

a supply bag including a supply solution,

wherein the pumping device is configured to move a dialysate solution through the dialysate circuit, allowing the dialysate solution that is stored in the mixing bag to flow through the dialyzer to perform a dialysis treatment, then through the sorbent device to remove some solute included in the dialysate solution, and then to reach the mixing bag again, and

wherein the pumping device is further configured to move the supply solution from the supply bag to the dialysate circuit by a supply line to reach the mixing bag and is the only means for pumping supply solution from the supply bag.

2. The system of claim 1 , wherein the supply solution is moved from the supply bag into the mixing bag of the dialysate circuit without passing through the dialyzer nor through the sorbent device.

3. The system of claim 1 , further comprising:

an electronic scale arranged to weigh the mixing bag.

4. The system of claim 3 , wherein the electronic scale weighs only the mixing bag.

5. The system of claim 3 , further comprising:

an electronic processor,

wherein the electronic processor is configured to receive data from the electronic scale and to determine at least one of an amount of ultrafiltrate removed during the treatment and an amount of the supply solution injected into the mixing bag.

6. The system of claim 1 , further comprising:

an electronic processor; and

a cassette which includes channels forming a part of the dialysate circuit and valves controlled by the electronic processor.

7. The system of claim 6 , wherein the cassette includes a first channel which is connected to an outlet of the mixing bag via a connection port and a valve, to an outlet of the supply bag via a connection port and a valve.

8. The system of claim 7 , wherein the first channel is further connected to an outlet of a dialysate supply bag via a connection port and with a dedicated valve.

9. The system of claim 7 , wherein the cassette includes a second channel in fluid communication with at least one of an inlet of the mixing bag, an inlet of a heater, and an inlet of the sorbent device.

10. The system of claim 9 , wherein the inlet of the mixing bag is connected to the cassette via a connection port and a valve.

11. The system of claim 9 , wherein the second channel is further connected to an inlet of the dialyzer via a connection port and a valve.

12. The system of claim 11 , wherein the electronic processor is configured to close the valve of dialyzer connected to the second channel when the valve of the supply bag connected to the first channel is open.

13. The system of claim 1 , further comprising:

an additional pumping device being part of the dialysate circuit for moving the dialysate solution in the dialysis circuit.

14. The system of claim 13 , wherein the additional pumping device is arranged between an outlet of the mixing bag and an inlet of the dialyzer.

15. The system of claim 13 , further comprising:

an electronic processor,

wherein the electronic processor is configured to control and monitor a speed of the pumping device and the additional pumping device to favor at least one of a diffusive clearance, a convective clearance, and a backfiltration.

16. The system of claim 1 , further comprising:

an electronic processor,

wherein the electronic processor is configured to control a pressure in a filtration device of a side of the dialysate to favor at least one of a diffusive clearance, a convective clearance, and a backfiltration.

17. The system of claim 1 , wherein the dialysate circuit includes a bypass.

18. The system of claim 17 , wherein the bypass allows a flow of a solution through the dialysate circuit without passing through the sorbent device.

19. The system of claim 17 , wherein the bypass allows a flow of a solution through the dialysate circuit without passing through a filtration device.

20. The system of claim 17 , wherein the bypass allows a flow of a solution through the dialysate circuit without passing through the pumping device.

21. The system of claim 1 , further comprising

a bypass for bypassing the dialysate circuit so that the pumping device can be operatively connected to the supply line.

22. The system of claim 1 , wherein the supply line is arranged such that the supply solution is moved from the supply bag to the mixing bag without passing through the sorbent device.

23. A method for purifying blood with a system including a dialysate circuit forming a loop circuit having a mixing bag, a dialyzer, and a sorbent device, a pumping device positioned in the loop circuit, and a supply bag including a supply solution, the method comprising the following steps:

first actuating the pumping device to move a dialysate solution through the dialysate circuit such that the dialysate solution flows through the dialyzer to perform a dialysis treatment, then through the sorbent device to remove some solute included in the dialysate solution, and then to the mixing bag; and

second actuating the pumping device to move a supply solution from the supply bag to the dialysate circuit by a supply line into the dialysate circuit to reach the mixing bag, wherein the pumping device is the only means for pumping supply solution from the supply bag.

24. The method of claim 23 , further comprising the step of:

bypassing the dialysate circuit so that the pumping device is operatively connected to the supply line, before the step of second actuating.

25. The method of claim 23 , wherein the supply line is arranged such that the supply solution is moved from the supply bag to the mixing bag without passing through the sorbent device.

26. A blood purification system comprising:

a dialysate circuit forming a loop circuit including a mixing bag, a dialyzer, and a sorbent device;

a pumping device positioned in the loop circuit; and

a supply bag including a supply solution having a dialysate solution or a regeneration solution,

wherein the pumping device is configured to move a dialysate solution through the dialysate circuit, allowing the dialysate solution to flow through the dialyzer to perform a dialysis treatment, through the sorbent device to remove some solute included in the dialysate solution, and

wherein the pumping device is further configured to move the supply solution from the supply bag to the dialysate circuit by a supply line and wherein the pumping device is the only means for pumping supply solution from the supply bag.

27. A blood purification system comprising:

a dialysate circuit forming a loop circuit including a mixing bag, a dialyzer, and a sorbent device;

a pumping device positioned in the loop circuit; and

a supply bag including a supply solution,

wherein the pumping device is configured to move a dialysate solution through the dialysate circuit, allowing the dialysate solution to flow through the dialyzer to perform a dialysis treatment, through the sorbent device to remove some solute included in the dialysate solution, and

wherein the pumping device is further configured to move the supply solution from the supply bag to the dialysate circuit by a supply line in order to reach the mixing bag without passing through the sorbent device and wherein the pumping device is the only means for pumping supply solution from the supply bag.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2020
From: DEBIOTECH S.A.
To: NEXTKIDNEY SA
Reel/Frame 051552/0644 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2020
From: THIEBAUD, PIERRE; NEFTEL, FRÉDÉRIC
To: DEBIOTECH S.A.
Reel/Frame 051542/0111 →
Priority Claims (1)
WO PCT/IB2014/061006 · Apr 25, 2014 · international
Continuity (1)
Related Publication 20170043078A1 · Feb 16, 2017
Cited By (1)
US 12,383,662