IP Library Granted Patent US 10,696,718
Granted Patent B2
US 10,696,718 · App. 16/030,541 · Granted Jun 30, 2020

Compstatin analogs for treatment of neuropathic pain

Inventors: Cedric Francois (Prospect, KY); Pascal Deschatelets (Prospect, KY)
Assignee: Apellis Pharmaceuticals, Inc.
C07K7/52A61F13/532A61F13/535A61K9/0019A61K38/10A61K38/12A61K38/16A61K45/06A61F2013/530554
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Quick Facts
Patent No.
US 10,696,718
App. No.
16/030,541
Granted
Jun 30, 2020
Kind
B2
Abstract

In some aspects, the present invention provides methods of treating a subject in need of treatment for neuropathic pain, the method comprising administering a compstatin analog to the subject. In some embodiments, the compstatin analog is administered parenterally, e.g., intravenously.

Claims (3)

1. A combination comprising a compstatin analog and a second agent useful for treating neuropathic pain, wherein the compstatin analog comprises the amino acid sequence of SEQ ID NO: 36.

2. The combination of claim 1 , wherein the compstatin analog consists of the amino acid sequence of SEQ ID NO: 36.

3. The combination of claim 1 , wherein the second agent is an antidepressant, anticonvulsant, NMDA antagonist, topical anesthetic, opioid analgesic, or sodium channel blocker.

Assignments (3)
RELEASE OF PATENT SECURITY AGREEMENT RECORDED AT REEL 067398 AND FRAME 0261 Recorded May 15, 2026
From: SIXTH STREET LENDING PARTNERS, IN ITS CAPACITY AS ADMINISTRATIVE AGENT
To: APELLIS PHARMACEUTICALS, INC.
Reel/Frame 075652/0212 →
SECURITY INTEREST Recorded May 13, 2024
From: APELLIS PHARMACEUTICALS, INC.
To: SIXTH STREET LENDING PARTNERS
Reel/Frame 067398/0261 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 2020
From: FRANCOIS, CEDRIC; DESCHATELETS, PASCAL
To: APELLIS PHARMACEUTICALS, INC.
Reel/Frame 052733/0172 →
Continuity (4)
Division 15209665 · Jul 13, 2016
Division 13805538
Provisional Application 61357448 · Jun 22, 2010
Related Publication 20190185515A1 · Jun 20, 2019